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Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Methylation Compound Library L3510 128 compounds Serotonin Receptor-Targeted Compound Library L2800 268 compounds DNA Damage & Repair Compound Library L3900 1040 compounds Ubiquitination Compound Library L8600 210 compounds NF-κB Signaling Compound Library L3800 729 compounds GPCR Compound Library L1500 2223 compounds Microtubule-Targeted Compound Library L1110 142 compounds AMPK-Targeted Compound Library L1120 80 compounds Sodium Channel Blocker Library L7400 118 compounds Histamine & Melatonin Receptor-Targeted Compound Library L3300 153 compounds Mitochondria-Targeted Compound Library L5300 812 compounds Cell Cycle Compound Library L8100 945 compounds Chemokine Inhibitor Library L7600 59 compounds Cytokine Inhibitor Library L3600 604 compounds TGF-beta/Smad Compound Library L4100 184 compounds Nuclear Receptor Compound Library L1510 531 compounds Autophagy Compound Library L3200 1248 compounds Wnt/Hedgehog/Notch Compound Library L4300 237 compounds Ferroptosis Compound Library L8700 779 compounds Pyroptosis Compound Library L8720 1066 compounds Adrenergic Receptor-Targeted Compound Library L2700 193 compounds Exosome Compound Library L9420 76 compounds Angiogenesis related Compound Library L4800 1353 compounds FDA-Approved Kinase Inhibitor Library L1610 263 compounds Calcium Channel Compound Library L7200 140 compounds Apoptosis Compound Library L9000 1760 compounds HIF-1 Signaling Pathway Compound Library L8500 1336 compounds Epigenetics Compound Library L1200 953 compounds Neurotransmitter Receptor Compound Library L2610 1660 compounds PI3K-AKT-mTOR Compound Library L1300 420 compounds Cuproptosis Compound Library L8710 400 compounds Protease Inhibitor Library L1100 343 compounds Potassium Channel Blocker Library L7300 152 compounds JAK-STAT Compound Library L3700 252 compounds MAPK Inhibitor Library L1400 365 compounds Tyrosine Kinase Inhibitor Library L2200 1016 compounds Kinase Inhibitor Library L1600 2840 compounds Endoplasmic Reticulum Stress Compound Library L9700 223 compounds GPCR Compound Library Plus L1580 338 compounds Cytoskeletal Signaling Pathway Compound Library L1310 759 compounds Inhibitor Library L2000 8328 compounds Phosphatase Inhibitor Library L9100 79 compounds Ion Channel Inhibitor Library L2300 1147 compounds Neuronal Signaling Compound Library L2600 2540 compounds