FDA-Approved Kinase Inhibitor Library

Product No.： L1610

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.

Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、RAF、EGFR、MEK、SAPK、GSK、MLCK、Src-family、IKK、PDGFR、VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

Product No.：L1610

Product Description

A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

Autophagy (72)

Apoptosis (57)

EGFR (35)

VEGFR (33)

c-Kit (32)

PDGFR (30)

JAK (18)

FGFR (18)

FLT (18)

Src (16)

Bcr-Abl (16)

c-Met/HGFR (14)

Tyrosine Kinases (14)

PKC (12)

CDK (12)

Raf (12)

ALK (11)

Others (10)

Mitophagy (10)

Antibacterial (10)

NF-κB (10)

PI3K (9)

Endogenous Metabolite (9)

AMPK (9)

c-RET (9)

Adrenergic Receptor (8)

BTK (8)

CaMK (8)

mTOR (8)

Sodium Channel (8)

Antibiotic (8)

Ferroptosis (7)

PKA (7)

Trk receptor (7)

5-HT Receptor (7)

MEK (7)

TAM Receptor (7)

Calcium Channel (6)

ERK (6)

ROCK (6)

Potassium Channel (6)

HER (6)

HIV Protease (5)

Histamine Receptor (5)

Parasite (5)

PDE (5)

ROS (5)

COX (5)

Akt (5)

AChR (5)

Ras (5)

ROS Kinase (5)

Dopamine Receptor (4)

p38 MAPK (4)

Antifungal (4)

GSK-3 (4)

Serine/threonin kinase (4)

Influenza Virus (4)

IκB/IKK (4)

Topoisomerase (3)

Glucosidase (3)

PAK (3)

IGF-1R (3)

SARS-CoV (3)

c-Fms (3)

P450 (3)

Syk (3)

FAK (3)

ROR (2)

Ligands for Target Protein for PROTAC (2)

LPL Receptor (2)

Adenosine Receptor (2)

NADPH (2)

Glutathione Peroxidase (2)

TOPK (2)

Phosphatase (2)

Serine Protease (2)

Serotonin Transporter (2)

IRE1 (2)

Hexokinase (2)

Aurora Kinase (2)

Lipoxygenase (2)

Interleukin (2)

DNA/RNA Synthesis (2)

MAPK (2)

P-gp (2)

Ephrin Receptor (2)

Nrf2 (2)

TNF (2)

Microtubule Associated (2)

Tyrosinase (2)

S1P Receptor (2)

PKM (2)

Chloride channel (1)

Proton pump (1)

Transferase (1)

DHFR (1)

DNA-PK (1)

HCV Protease (1)

Integrin (1)

Estrogen/progestogen Receptor (1)

Dehydrogenase (1)

YAP (1)

Antioxidant (1)

IFNAR (1)

JNK (1)

gp120/CD4 (1)

Virus Protease (1)

Melatonin Receptor (1)

HBV (1)

PPAR (1)

Hck (1)

Antifolate (1)

Nucleoside Antimetabolite/Analog (1)

Caspase (1)

TRP/TRPV Channel (1)

CSF-1R (1)

LDL (1)

GRK (1)

Phosphorylase (1)

Mitochondrial Metabolism (1)

Monoamine Transporter (1)

Reactive Oxygen Species (1)

HSV (1)

IL Receptor (1)

Chk (1)

PAD (1)

ACK (1)

GluR (1)

Norepinephrine (1)

DNA (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

TGF-beta/Smad (1)

ATP Citrate Lyase (1)

AChE (1)

Antiviral (1)

Sirtuin (1)

Beta Amyloid (1)

HDAC (1)

Hydroxylase (1)

PLK (1)

Gap Junction Protein (1)

Anti-infection (1)

NADPH-oxidase (1)

S6 Kinase (1)

Sigma receptor (1)

HIF/HIF Prolyl-Hydroxylase (1)

NO Synthase (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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