Autophagy Compound Library

Product No.： L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1248 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

Product No.：L3200

Product Description

A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
Bioactivity and safety confirmed by pre-clinical research and clinical trials;
Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

PI3K (99)

Antibacterial (92)

Others (88)

mTOR (72)

Endogenous Metabolite (67)

Antibiotic (65)

Mitophagy (54)

AMPK (46)

p38 MAPK (41)

HIV Protease (40)

Ferroptosis (39)

Akt (39)

HDAC (39)

NF-κB (39)

Parasite (34)

Reactive Oxygen Species (34)

CXCR (31)

Raf (30)

Calcium Channel (27)

Potassium Channel (27)

VEGFR (26)

Adrenergic Receptor (24)

CDK (23)

Aurora Kinase (23)

COX (23)

Retinoid Receptor (23)

DNA-PK (22)

ERK (22)

EGFR (22)

MEK (22)

p53 (22)

DNA/RNA Synthesis (21)

Bcr-Abl (20)

Influenza Virus (20)

P450 (20)

FLT (20)

c-Kit (20)

PDGFR (19)

Src (17)

PKC (17)

Topoisomerase (17)

LRRK2 (17)

5-HT Receptor (17)

AChR (17)

Antifungal (16)

GSK-3 (16)

Virus Protease (16)

CFTR (16)

PKA (15)

CaMK (15)

SARS-CoV (15)

Proteasome (14)

JNK (14)

BCL (14)

FGFR (14)

FXR (13)

E1/E2/E3 Enzyme (13)

FAAH (13)

TNF (13)

HMG-CoA Reductase (13)

S6 Kinase (13)

JAK (12)

Sirtuin (12)

STAT (12)

Sodium Channel (12)

Ras (12)

Microtubule Associated (12)

Dopamine Receptor (11)

Estrogen/progestogen Receptor (11)

PPAR (11)

PDE (11)

HSV (11)

MMP (11)

HIF/HIF Prolyl-Hydroxylase (11)

PERK (10)

Serine/threonin kinase (10)

Caspase (10)

Epigenetic Reader Domain (10)

DUB (10)

TLR (10)

Nrf2 (10)

ATM/ATR (10)

c-RET (10)

Mdm2 (9)

Dehydrogenase (9)

Mitochondrial Metabolism (9)

TGF-beta/Smad (9)

Casein Kinase (9)

Antioxidant (8)

Phosphatase (8)

PARP (8)

Nucleoside Antimetabolite/Analog (8)

TRP/TRPV Channel (8)

ROCK (8)

HIF (8)

ATPase (7)

Proton pump (7)

Histone Methyltransferase (7)

c-Met/HGFR (7)

Histamine Receptor (7)

Glucocorticoid Receptor (7)

HSP (7)

Trk receptor (7)

IκB/IKK (7)

c-Myc (6)

Estrogen Receptor/ERR (6)

Tyrosine Kinases (6)

MAO (6)

IL Receptor (6)

PTEN (6)

Lipoxygenase (6)

IGF-1R (6)

P-gp (6)

ALK (6)

Beta Amyloid (6)

GABA Receptor (6)

NADPH (5)

Wnt/beta-catenin (5)

Rho (5)

Cysteine Protease (5)

ROS (5)

ribosome (5)

PDK (5)

Phospholipase (5)

HER (5)

NOS (4)

Carbonic Anhydrase (4)

DHFR (4)

HCV Protease (4)

Integrin (4)

DNA Alkylator/Crosslinker (4)

Progesterone Receptor (4)

MRP (4)

Serine Protease (4)

Serotonin Transporter (4)

Glucokinase (4)

Aryl Hydrocarbon Receptor (4)

IAP (4)

Gamma-secretase (4)

Opioid Receptor (4)

DPP-4 (4)

Hedgehog/Smoothened (4)

GluR (4)

Prostaglandin Receptor (4)

transporter (4)

Reverse Transcriptase (4)

c-Fms (4)

DNA Methyltransferase (4)

FAK (4)

ROS Kinase (4)

Transferase (3)

Dynamin (3)

Amino Acids and Derivatives (3)

Adenosine Receptor (3)

RAAS (3)

ABC (3)

HBV (3)

Pim (3)

Antifolate (3)

SIK (3)

RIP kinase (3)

P2X Receptor (3)

Molecular Glues (3)

Fatty Acid Synthase (3)

DNA (3)

Androgen Receptor (3)

Ligand for E3 Ligase (3)

PLK (3)

SGK (3)

Cannabinoid Receptor (3)

Monoamine Oxidase (3)

NO Synthase (3)

ROR (2)

Ligands for Target Protein for PROTAC (2)

YAP (2)

BACE (2)

DYRK (2)

Cell wall (2)

Glutathione Peroxidase (2)

GTPase (2)

VDA (2)

iGluR (2)

IRE1 (2)

LDL (2)

Drug Metabolite (2)

NMDAR (2)

BTK (2)

Antifection (2)

DNA Alkylation (2)

PGC-1α (2)

CCR (2)

Chk (2)

Norepinephrine (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Interleukin (2)

MAPK (2)

AChE (2)

MNK (2)

Antiviral (2)

Histone Acetyltransferase (2)

CRISPR/Cas9 (2)

GPR (2)

ATTECs (2)

Syk (2)

NOD (2)

BMI-1 (2)

TAM Receptor (2)

Tyrosinase (2)

p97 (2)

lysosomal autophagy (2)

AhR (2)

NOD-like Receptor (NLR) (2)

MLK (2)

S1P Receptor (2)

Adenylyl cyclase (1)

CAT (1)

NPC1L1 (1)

MyD88 (1)

Arginase (1)

LPL Receptor (1)

LTR (1)

Reductase (1)

IFNAR (1)

Arrestin (1)

Na+/Ca2+ Exchanger (1)

RAR/RXR (1)

Histone Demethylase (1)

Lipase (1)

Tie-2 (1)

TOPK (1)

Factor Xa (1)

Melatonin Receptor (1)

Liver X Receptor (1)

Leukotriene Receptor (1)

NAMPT (1)

Glutaminase (1)

FOXO1 (1)

IDO (1)

CSF-1R (1)

Myosin (1)

Annexin A (1)

UGT (1)

PAFR (1)

GRK (1)

DNA gyrase (1)

Glucosidase (1)

Hexokinase (1)

Monoamine Transporter (1)

Guanylate cyclase (1)

Smo (1)

PROTAC Linker (1)

Endothelin Receptor (1)

Somatostatin (1)

ACK (1)

Lipid (1)

ATP Citrate Lyase (1)

OXPHOS (1)

BCRP (1)

Beta-Secretase (1)

Survivin (1)

STING (1)

Aminopeptidase (1)

GPCR19 (1)

Ephrin Receptor (1)

GluCls (1)

PAI-1 (1)

PI4K (1)

Complement System (1)

Gap Junction Protein (1)

Anti-infection (1)

IRAK (1)

Sigma receptor (1)

Thrombin (1)

Imidazoline Receptor (1)

PD-1/PD-L1 (1)

Kinesin (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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