Kinase Inhibitor Library

Product No.： L1600

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules (ATP) to specific substrates. This process is known as phosphorylation. The protein kinases make up the majority of all kinases and are widely studied. A protein kinase modifies other molecules, mostly proteins, by phosphorylation to regulate the majority of cellular pathways, especially those involved in signal transduction. Various other kinases act on small molecules such as lipids, carbohydrates, amino acids, and nucleotides, either for signaling or to prime them for metabolic pathways.

TargetMol’s Kinase Inhibitor Library, containing 2720 kinase inhibitors/regulators , can be used for research in chemical genomics, pharmacological study, and drug screening for related diseases.

Product No.：L1600

Product Description

A unique collection of 2720 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

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Compound library Consultation

Composition of compound library

EGFR (191)

VEGFR (160)

Others (120)

mTOR (112)

JAK (111)

ERK (104)

Akt (104)

p38 MAPK (102)

FLT (101)

Src (100)

PDGFR (92)

PKC (88)

AMPK (84)

GSK-3 (83)

FGFR (83)

Raf (81)

c-Kit (75)

Ras (74)

NF-κB (71)

c-Met/HGFR (69)

Bcr-Abl (66)

ALK (58)

Aurora Kinase (57)

MAPK (57)

BTK (55)

JNK (52)

PKA (49)

MEK (49)

Tyrosine Kinases (48)

ROCK (48)

Casein Kinase (47)

Serine/threonin kinase (41)

Endogenous Metabolite (41)

IGF-1R (40)

Antibacterial (40)

DNA-PK (38)

c-RET (38)

TAM Receptor (38)

Epigenetic Reader Domain (36)

Glucosidase (34)

CaMK (34)

Trk receptor (34)

IκB/IKK (34)

FAK (33)

S6 Kinase (32)

RIP kinase (31)

TGF-beta/Smad (31)

PLK (31)

Glucokinase (30)

ATM/ATR (30)

STAT (30)

HER (30)

c-Fms (28)

TNF (28)

Syk (28)

Parasite (27)

Chk (26)

Pim (25)

PERK (24)

ROR (23)

IRAK (22)

Caspase (21)

DYRK (20)

COX (20)

LRRK2 (20)

PDK (20)

Mitophagy (19)

Antibiotic (19)

HIV Protease (18)

PAK (18)

Influenza Virus (18)

Wnt/beta-catenin (17)

Rho (17)

Reactive Oxygen Species (16)

PI4K (16)

IRE1 (15)

IL Receptor (15)

DNA/RNA Synthesis (15)

Tyrosinase (15)

Ferroptosis (14)

Calcium Channel (14)

Ephrin Receptor (14)

ROS Kinase (14)

Phosphatase (13)

AChR (13)

Antifungal (12)

PPAR (12)

BCL (12)

MMP (12)

5-HT Receptor (12)

Adrenergic Receptor (11)

CSF-1R (11)

P450 (11)

Potassium Channel (11)

Dehydrogenase (10)

PDE (10)

GRK (10)

ROS (10)

MNK (10)

Discoidin Domain Receptor (DDR) (10)

MLK (10)

S1P Receptor (10)

Kinesin (10)

Adenosine Receptor (9)

Serine Protease (9)

HSV (9)

SGK (9)

Microtubule Associated (9)

PKM (9)

NO Synthase (9)

PARP (8)

LIM Kinase (8)

Wee1 (8)

Antiviral (8)

SARS-CoV (8)

Beta Amyloid (8)

HDAC (8)

Sodium Channel (8)

Tie-2 (7)

Virus Protease (7)

SIK (7)

AAK1 (AP2 associated kinase 1) (7)

Mitochondrial Metabolism (7)

Lipoxygenase (7)

Interleukin (7)

AChE (7)

HCV Protease (6)

Histamine Receptor (6)

Topoisomerase (6)

Drug Metabolite (6)

P-gp (6)

Nrf2 (6)

MELK (6)

Dopamine Receptor (5)

Histone Methyltransferase (5)

Integrin (5)

Antioxidant (5)

TOPK (5)

PYK2 (5)

LDL (5)

Antifection (5)

ACK (5)

TLR (5)

transporter (5)

ASK (5)

Hippo pathway (5)

Ligand for E3 Ligase (5)

Carbonic Anhydrase (4)

Estrogen/progestogen Receptor (4)

LPL Receptor (4)

GTPase (4)

Myosin (4)

GluR (4)

Carboxypeptidase (4)

DAPK (4)

ATPase (3)

NOS (3)

Transferase (3)

Ligands for Target Protein for PROTAC (3)

YAP (3)

BACE (3)

IFNAR (3)

NADPH (3)

Glutathione Peroxidase (3)

Estrogen Receptor/ERR (3)

HBV (3)

Hck (3)

TRP/TRPV Channel (3)

MAO (3)

Aryl Hydrocarbon Receptor (3)

E1/E2/E3 Enzyme (3)

Haspin Kinase (3)

Hexokinase (3)

DNA Alkylation (3)

Indoleamine 2,3-Dioxygenase (IDO) (3)

HSP (3)

Prostaglandin Receptor (3)

Sirtuin (3)

PAI-1 (3)

Phospholipase (3)

cholecystokinin (3)

HIF/HIF Prolyl-Hydroxylase (3)

p53 (3)

Chloride channel (2)

PROTACs (2)

RAAS (2)

Serotonin Transporter (2)

Nucleoside Antimetabolite/Analog (2)

FXR (2)

Gamma-secretase (2)

PTEN (2)

cAMP (2)

DUB (2)

BCRP (2)

Beta-Secretase (2)

Histone Acetyltransferase (2)

Reverse Transcriptase (2)

CRISPR/Cas9 (2)

GPR (2)

HIF (2)

Cannabinoid Receptor (2)

Anti-infection (2)

NADPH-oxidase (2)

Proteasome (1)

Proton pump (1)

NPC1L1 (1)

DHFR (1)

MyD88 (1)

Arrestin (1)

RAR/RXR (1)

Histone Demethylase (1)

CETP (1)

Necroptosis (1)

gp120/CD4 (1)

Melatonin Receptor (1)

MRP (1)

Antifolate (1)

cell cycle arrest (1)

Liver X Receptor (1)

NAMPT (1)

Stemness kinase (1)

iGluR (1)

Phosphorylase (1)

P2X Receptor (1)

NMDAR (1)

Monoamine Transporter (1)

Opioid Receptor (1)

PROTAC Linker (1)

Fatty Acid Synthase (1)

Bombesin Receptor (1)

Hedgehog/Smoothened (1)

FAAH (1)

PAD (1)

Thrombopoietin Receptor (1)

Norepinephrine (1)

DNA (1)

Lipid (1)

ATP Citrate Lyase (1)

PGE Synthase (1)

Acyltransferase (1)

Porcupine (1)

STING (1)

Decarboxylase (1)

cGAS (1)

RSV (1)

GPX (1)

Retinoid Receptor (1)

Protease (1)

Aromatase (1)

GABA Receptor (1)

Hydroxylase (1)

RXFP receptor (1)

Gap Junction Protein (1)

Fer/FerT kinase (1)

BMI-1 (1)

Sigma receptor (1)

Protease-activated Receptor (1)

p97 (1)

AhR (1)

PD-1/PD-L1 (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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