Cell Cycle Compound Library

Product No.： L8100

Cell cycle, the ordered sequence of events that occur in a cell in preparation for cell division, is also divided into two periods: interphase and the mitotic (M) phase. Interphase itself is split into different phases: G1 phase, S phase and G2 phase. Cell Cycle related compounds rely on differing mechanisms of action to regulate the normal progression of the cell cycle. Some of these compounds interfere with CDK/cyclin complexes leaving cells stuck at the G2/M phase border, while others affect CaMKII phosphorylation, inducing arrest at the G1 phase. Other mechanisms of action include interference with RNA function and inhibition of protein synthesis. Many of these compounds ultimately induce apoptosis as a result of their interruption of the cell cycle. This library can be used for anti-cancer drug screening.

The TargetMol’s Cell Cycle Compound Library, a unique collection of 677 cell cycle related compounds, can be used for research in cell cycle and related drug screening.

Product No.：L8100

Product Description

A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.;
Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc.;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC/LCMS validated to ensure high purity and quality;

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

DNA/RNA Synthesis (180)

CDK (142)

Apoptosis (140)

Autophagy (92)

Ferroptosis (87)

Others (65)

Nucleoside Antimetabolite/Analog (42)

Aurora Kinase (41)

Antibacterial (39)

Antibiotic (35)

Endogenous Metabolite (33)

DUB (32)

ROCK (31)

Serine/threonin kinase (29)

PLK (21)

Chk (19)

FLT (18)

Ras (16)

GSK-3 (15)

c-Myc (15)

Dehydrogenase (14)

Parasite (14)

Antifolate (14)

PKC (14)

Influenza Virus (14)

Src (13)

Rho (13)

VEGFR (13)

IRE1 (13)

DHFR (12)

HSV (12)

PKA (11)

HIV Protease (10)

JAK (10)

SARS-CoV (10)

PD-1/PD-L1 (10)

Antifungal (9)

DYRK (9)

PDGFR (9)

Nrf2 (9)

Mitophagy (8)

ERK (8)

Topoisomerase (8)

Reactive Oxygen Species (8)

Akt (8)

FGFR (8)

DNA Alkylator/Crosslinker (7)

Bcr-Abl (7)

Lipoxygenase (7)

Epigenetic Reader Domain (7)

Casein Kinase (7)

NF-κB (7)

c-RET (7)

c-Kit (7)

S6 Kinase (7)

Antioxidant (6)

Virus Protease (6)

PPAR (6)

APC (6)

IκB/IKK (6)

STAT (6)

p38 MAPK (5)

LIM Kinase (5)

Raf (5)

COX (5)

EGFR (5)

Trk receptor (5)

MEK (5)

BMI-1 (5)

HMG-CoA Reductase (5)

p53 (5)

Proteasome (4)

JNK (4)

HBV (4)

Tyrosine Kinases (4)

Serine Protease (4)

cell cycle arrest (4)

DPP-4 (4)

SGK (4)

ATPase (3)

HCV Protease (3)

c-Met/HGFR (3)

PI3K (3)

Glutathione Peroxidase (3)

Wnt/beta-catenin (3)

Calcium Channel (3)

Drug Metabolite (3)

Mitochondrial Metabolism (3)

ROS (3)

BCL (3)

KSP (3)

GluR (3)

IGF-1R (3)

TGF-beta/Smad (3)

Wee1 (3)

LRRK2 (3)

GPX (3)

Reverse Transcriptase (3)

PDK (3)

DNA Methyltransferase (3)

HIF/HIF Prolyl-Hydroxylase (3)

Kinesin (3)

Carbonic Anhydrase (2)

DNA-PK (2)

Amino Acids and Derivatives (2)

Arginase (2)

NADPH (2)

PYK2 (2)

Caspase (2)

TRP/TRPV Channel (2)

iGluR (2)

MTH1 (2)

Haspin Kinase (2)

GRK (2)

DNA gyrase (2)

Antifection (2)

DNA Alkylation (2)

DNA (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

mTOR (2)

Interleukin (2)

MAPK (2)

Histone Acetyltransferase (2)

ATM/ATR (2)

Carboxypeptidase (2)

ribosome (2)

KLF (2)

AMPK (2)

5-HT Receptor (2)

P450 (2)

AChR (2)

Syk (2)

Sodium Channel (2)

TAM Receptor (2)

cholecystokinin (2)

FAK (2)

Proton pump (1)

Dopamine Receptor (1)

Histone Methyltransferase (1)

YAP (1)

P2Y Receptor (1)

Adenosine Receptor (1)

PERK (1)

Histamine Receptor (1)

Tie-2 (1)

TOPK (1)

Phosphatase (1)

OCT (1)

Pim (1)

Cysteine Protease (1)

Glucokinase (1)

Aryl Hydrocarbon Receptor (1)

MAO (1)

Myosin (1)

E1/E2/E3 Enzyme (1)

RIP kinase (1)

UGT (1)

BTK (1)

Opioid Receptor (1)

IL Receptor (1)

CXCR (1)

Xanthine Oxidase (1)

CaMK (1)

Telomerase (1)

MNK (1)

P-gp (1)

Antiviral (1)

HSP (1)

Free radical scavengers (1)

Sirtuin (1)

PAI-1 (1)

RSV (1)

GST (1)

Beta Amyloid (1)

Ligand for E3 Ligase (1)

HDAC (1)

c-Fms (1)

GPR (1)

CRISPR/Cas9 (1)

Phospholipase (1)

GABA Receptor (1)

HIF (1)

Potassium Channel (1)

NADPH-oxidase (1)

IRAK (1)

Sigma receptor (1)

Tyrosinase (1)

lysosomal autophagy (1)

NOD-like Receptor (NLR) (1)

MLK (1)

NO Synthase (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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