Potassium Channel Blocker Library

Product No.： L7300

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore, potassium channels are found in most cell types and control a wide variety of cell functions, such as regulation of cellular excitability, neurotransmitter release, protecting cardiac myocytes, and anti-arrhythmia function, and are involved in learning and memory process, and temperature control. Potassium channel blockers is a class of drugs that act by inhibition of potassium efflux through cell membranes, including inorganic ions (Cs, Ba) and organic molecules (TEA, 4-AP), toxins (scorpion venoms, snake venoms, and bee venoms), and potassium channel blockers in clinical use.

Product No.：L7300

Product Description

A unique collection of 152 potassium channel blockers and agonists for high throughput and high content screening;
Targeting different subtypes of potassium channels, such as Kir1.1, Kir3.x, Kir6.x and Kv7.1, etc.
Bioactivity and safety confirmed by pre-clinical research and clinical trials, some of which are FDA approved;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

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Compound library Consultation

Composition of compound library

Potassium Channel (152)

Autophagy (22)

Sodium Channel (16)

Calcium Channel (10)

Others (8)

Adrenergic Receptor (7)

Parasite (7)

5-HT Receptor (7)

HER (7)

AChR (6)

ATPase (5)

Antibacterial (5)

Apoptosis (5)

Dopamine Receptor (4)

EGFR (4)

COX (4)

P450 (4)

ABC (3)

iGluR (3)

MRP (3)

PPAR (3)

Antibiotic (3)

Endogenous Metabolite (3)

Chloride channel (2)

Carbonic Anhydrase (2)

NADPH (2)

Histamine Receptor (2)

Antifungal (2)

TRP/TRPV Channel (2)

Topoisomerase (2)

NMDAR (2)

Drug Metabolite (2)

Reactive Oxygen Species (2)

NF-κB (2)

AMPK (2)

TNF (2)

GPR (2)

NOS (1)

Estrogen/progestogen Receptor (1)

JNK (1)

GSK-3 (1)

Proteasome (1)

Integrin (1)

Na+/Ca2+ Exchanger (1)

Estrogen Receptor/ERR (1)

VEGFR (1)

Caspase (1)

PDE (1)

LDL (1)

DNA gyrase (1)

Mitochondrial Metabolism (1)

FXR (1)

PKC (1)

ERK (1)

Antifection (1)

Monoamine Transporter (1)

IL Receptor (1)

CXCR (1)

GluR (1)

CaMK (1)

DNA (1)

BCRP (1)

DNA/RNA Synthesis (1)

P-gp (1)

SARS-CoV (1)

mTOR (1)

IκB/IKK (1)

Beta Amyloid (1)

HMG-CoA Reductase (1)

CFTR (1)

NO Synthase (1)

PAI-1 (1)

STAT (1)

GABA Receptor (1)

Gap Junction Protein (1)

Platelet aggregation (1)

NOD (1)

Thrombin (1)

NOD-like Receptor (NLR) (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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