Protease Inhibitor Library

Product No.： L1100

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer.

The Protease Inhibitor Library by TargetMol, containing 343 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

Product No.：L1100

Product Description

A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

MMP (57)

Proteasome (48)

Tyrosinase (48)

Caspase (47)

Apoptosis (44)

Autophagy (30)

HIV Protease (29)

Gamma-secretase (29)

Cysteine Protease (28)

Serine Protease (24)

SARS-CoV (24)

DPP-4 (23)

Others (22)

Antibacterial (20)

Thrombin (17)

HCV Protease (14)

Endogenous Metabolite (12)

NF-κB (11)

BCL (9)

p38 MAPK (8)

Parasite (8)

PARP (8)

COX (8)

Beta Amyloid (8)

Serine/threonin kinase (7)

TNF (7)

Virus Protease (6)

PPAR (6)

ERK (6)

Akt (6)

BACE (5)

Glutaminase (5)

P450 (5)

Ferroptosis (4)

Antifungal (4)

Factor Xa (4)

VEGFR (4)

Reactive Oxygen Species (4)

Beta-Secretase (4)

P-gp (4)

Influenza Virus (4)

AMPK (4)

GABA Receptor (4)

Antibiotic (4)

Antioxidant (3)

Histamine Receptor (3)

JNK (3)

Mitophagy (3)

HSV (3)

IL Receptor (3)

Lipoxygenase (3)

DUB (3)

Interleukin (3)

Prostaglandin Receptor (3)

transporter (3)

HDAC (3)

AChR (3)

Anti-infection (3)

Estrogen/progestogen Receptor (2)

PI3K (2)

Phosphatase (2)

IAP (2)

Immunology/Inflammation related (2)

CDK (2)

Drug Metabolite (2)

Free radical scavengers (2)

PAI-1 (2)

ribosome (2)

5-HT Receptor (2)

Potassium Channel (2)

Platelet aggregation (2)

Sodium Channel (2)

NO Synthase (2)

ATPase (1)

Proton pump (1)

ROR (1)

Src (1)

Amino Acids and Derivatives (1)

Na+/Ca2+ Exchanger (1)

Tyrosine Kinases (1)

Calcium Channel (1)

PKC (1)

Adrenergic Receptor (1)

Topoisomerase (1)

E1/E2/E3 Enzyme (1)

UGT (1)

Glucosidase (1)

PDGFR (1)

JAK (1)

CXCR (1)

Aurora Kinase (1)

IGF-1R (1)

DNA (1)

CaMK (1)

EGFR (1)

MAPK (1)

Antiviral (1)

TLR (1)

Sirtuin (1)

Pyroptosis (1)

ALK (1)

IκB/IKK (1)

STAT (1)

Protease (1)

Phospholipase (1)

c-Kit (1)

Ras (1)

Microtubule Associated (1)

p53 (1)

HER (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
{{item.packagingtext}}