Inhibitor Library

Product No.： L2000

Cell signalingis part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, andimmunity, as well as normal tissuehomeostasis. Errors in signaling interactions and cellularinformation processingare responsible for diseases such as cancer,auto-immunity, and diabetes.By understanding cell signaling, diseases may be treated more effectively.

Inhibitor library is a unique collection of 8328 compounds, each of which has clear inhibitory targets. It is an effective tool for research in cell signaling pathways and related diseases, and high throughput screening and high content screening for new drugs.

Product No.：L2000

Product Description

A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;
Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
Covers various major targets including MAPK, PI3K, JAK, HDAC, VEGFR, CDK, etc.;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

COX (185)

PI3K (178)

Endogenous Metabolite (174)

Antibiotic (172)

EGFR (170)

HIV Protease (167)

AChR (161)

DNA/RNA Synthesis (160)

VEGFR (154)

PDE (151)

NF-κB (151)

Epigenetic Reader Domain (141)

Dopamine Receptor (140)

Dehydrogenase (134)

Adrenergic Receptor (124)

P450 (122)

Histone Methyltransferase (121)

Histamine Receptor (117)

HDAC (117)

Parasite (116)

Potassium Channel (111)

Calcium Channel (109)

JAK (102)

mTOR (99)

Antifungal (98)

FLT (98)

Phosphatase (96)

Sodium Channel (94)

Src (93)

PDGFR (89)

Microtubule Associated (86)

Topoisomerase (81)

TRP/TRPV Channel (80)

PARP (79)

FGFR (79)

Raf (78)

AChE (77)

Wnt/beta-catenin (75)

c-Kit (75)

ERK (74)

SARS-CoV (74)

PKC (73)

Influenza Virus (73)

Akt (72)

p38 MAPK (71)

GSK-3 (71)

HCV Protease (69)

STAT (69)

MAO (66)

Ras (66)

c-Met/HGFR (65)

RAAS (63)

Bcr-Abl (62)

Prostaglandin Receptor (62)

Proteasome (60)

TNF (59)

Lipoxygenase (58)

Reactive Oxygen Species (57)

Aurora Kinase (57)

Ferroptosis (56)

ALK (56)

GABA Receptor (56)

MMP (55)

Phospholipase (55)

BCL (53)

HSP (53)

BTK (52)

DUB (51)

TGF-beta/Smad (49)

Virus Protease (48)

Transferase (46)

Adenosine Receptor (46)

ROCK (46)

Casein Kinase (46)

Tyrosine Kinases (45)

MAPK (45)

Tyrosinase (45)

NMDAR (44)

MEK (44)

E1/E2/E3 Enzyme (43)

Monoamine Oxidase (43)

ATPase (42)

GluR (42)

Histone Demethylase (41)

Serine/threonin kinase (41)

Caspase (41)

Beta Amyloid (41)

NO Synthase (41)

HER (41)

iGluR (39)

HSV (39)

IL Receptor (39)

DNA-PK (38)

JNK (38)

PKA (38)

CCR (38)

Reverse Transcriptase (38)

Carbonic Anhydrase (37)

PPAR (37)

Sirtuin (37)

GPR (37)

c-RET (37)

Mitophagy (36)

Serotonin Transporter (36)

Cysteine Protease (36)

Mitochondrial Metabolism (36)

AMPK (36)

IκB/IKK (35)

TAM Receptor (35)

Antioxidant (34)

HBV (34)

Integrin (33)

Nucleoside Antimetabolite/Analog (33)

IGF-1R (33)

NOS (32)

Gamma-secretase (32)

P-gp (32)

HIF (32)

RIP kinase (31)

ROS (31)

Serine Protease (30)

Drug Metabolite (30)

CXCR (30)

Norepinephrine (30)

Glucosidase (29)

TLR (29)

Histone Acetyltransferase (29)

c-Fms (29)

S6 Kinase (29)

HIF/HIF Prolyl-Hydroxylase (29)

Estrogen/progestogen Receptor (28)

Reductase (28)

CaMK (28)

Androgen Receptor (28)

PLK (28)

Proton pump (27)

Estrogen Receptor/ERR (27)

Interleukin (27)

Trk receptor (27)

P2X Receptor (26)

FAAH (26)

Pim (25)

Hedgehog/Smoothened (25)

Antiviral (25)

Syk (25)

DPP-4 (24)

Acyltransferase (24)

ATM/ATR (24)

FAK (24)

p53 (24)

Glucocorticoid Receptor (23)

Chk (23)

Kinesin (23)

Fatty Acid Synthase (22)

Indoleamine 2,3-Dioxygenase (IDO) (22)

Opioid Receptor (21)

SGLT (21)

Cannabinoid Receptor (21)

NOD (21)

HMG-CoA Reductase (21)

Thrombin (21)

DYRK (20)

NADPH (20)

Anti-infection (20)

IRAK (20)

Mdm2 (19)

Chloride channel (19)

Xanthine Oxidase (19)

LRRK2 (19)

transporter (19)

PDK (19)

DNA Methyltransferase (19)

LPL Receptor (18)

Lipase (18)

Rho (18)

Antifection (18)

Neurokinin receptor (18)

S1P Receptor (18)

Factor Xa (17)

MRP (17)

Smo (17)

PAK (17)

Endothelin Receptor (17)

Nrf2 (17)

Epoxide Hydrolase (16)

Hydroxylase (16)

PD-1/PD-L1 (16)

P2Y Receptor (15)

LTR (15)

BACE (15)

PERK (15)

Glutathione Peroxidase (15)

PI4K (15)

YAP (14)

Glucokinase (14)

CSF-1R (14)

Immunology/Inflammation related (14)

IRE1 (14)

OX Receptor (14)

Retinoid Receptor (14)

ribosome (14)

Aromatase (14)

Complement System (14)

DHFR (13)

GTPase (13)

c-Myc (13)

Leukotriene Receptor (13)

Myosin (13)

cAMP (13)

Sigma receptor (13)

ROS Kinase (13)

Aryl Hydrocarbon Receptor (12)

Neuropeptide Y Receptor (12)

PGE Synthase (12)

Aminopeptidase (12)

Ephrin Receptor (12)

LPA Receptor (12)

Protease-activated Receptor (12)

DNA gyrase (11)

Monoamine Transporter (11)

Isocitrate Dehydrogenase (IDH) (11)

Stearoyl-CoA Desaturase (SCD) (11)

Lipid (11)

Beta-Secretase (11)

Discoidin Domain Receptor (DDR) (11)

AhR (11)

NOD-like Receptor (NLR) (11)

Monocarboxylate transporter (10)

CETP (10)

Antifolate (10)

IDO (10)

DNA (10)

PAI-1 (10)

Acetyl-CoA Carboxylase (10)

cholecystokinin (10)

Glutaminase (9)

IAP (9)

GRK (9)

Vasopressin Receptor (9)

Telomerase (9)

ATP Citrate Lyase (9)

MNK (9)

STING (9)

SGK (9)

MLK (9)

NAMPT (8)

Phosphorylase (8)

BCRP (8)

Porcupine (8)

ASK (8)

RSV (8)

Neprilysin (8)

Platelet aggregation (8)

NADPH-oxidase (8)

CFTR (8)

Adenylyl cyclase (7)

Dynamin (7)

Na+/Ca2+ Exchanger (7)

Tie-2 (7)

ABC (7)

SIK (7)

UGT (7)

GlyT (7)

MAGL (7)

Angiotensin-converting Enzyme (ACE) (7)

PAD (7)

Wee1 (7)

Carboxypeptidase (7)

GPX (7)

p97 (7)

Thyroid hormone receptor(THR) (6)

DNA Alkylator/Crosslinker (6)

Progesterone Receptor (6)

FLAP (6)

LDL (6)

AAK1 (AP2 associated kinase 1) (6)

Guanylate cyclase (6)

DNA Alkylation (6)

OAT (6)

MELK (6)

GST (6)

NPC1L1 (5)

CRM1 (5)

DprE1 (5)

LIM Kinase (5)

Neurotensin Receptor (5)

PYK2 (5)

PAFR (5)

MTH1 (5)

APC (5)

Bombesin Receptor (5)

ACK (5)

Survivin (5)

Decarboxylase (5)

cGAS (5)

CRFR (5)

Methionine Adenosyltransferase (MAT) (5)

Hippo pathway (5)

Melanocortin Receptor (5)

CRISPR/Cas9 (5)

Aquaporin (5)

Adenosine deaminase (5)

BMI-1 (5)

advanced glycation end products (4)

MALT (4)

ROR (4)

NEDD8 (4)

MyD88 (4)

Amino Acids and Derivatives (4)

TOPK (4)

Galectin (4)

GNRH Receptor (4)

VDAC (4)

Amylase (4)

MT Receptor (4)

Glucagon Receptor (4)

Bradykinin Receptor (4)

PTEN (4)

KSP (4)

CD73 (4)

Protease (4)

CGRP Receptor (4)

DAPK (4)

Imidazoline Receptor (4)

PKM (4)

CAT (3)

Transaminase (3)

Arginase (3)

IFNAR (3)

Necroptosis (3)

Melatonin Receptor (3)

CaSR (3)

Hck (3)

Liver X Receptor (3)

Haspin Kinase (3)

Hexokinase (3)

HCN Channel (3)

OXPHOS (3)

Pyroptosis (3)

Ligand for E3 Ligase (3)

Gap Junction Protein (3)

Melanin-concentrating Hormone Receptor (MCHR) (2)

GSNOR (2)

CD38 (2)

NUDIX hydrolase (2)

EBI2/GPR183 (2)

Arrestin (2)

gp120/CD4 (2)

FXR (2)

FOXO1 (2)

Prolyl Endopeptidase (PREP) (2)

Na-K-Cl cotransporter (2)

Integrase (2)

AIM2 (2)

hCE (2)

KLF (2)

Oxytocin Receptor (2)

GHSR (2)

Apelin receptor (1)

Taste receptor (1)

stilbene oxidase (1)

Ligands for Target Protein for PROTAC (1)

Procollagen C Proteinase (1)

aconitase (1)

Neuropeptide W (1)

RAR/RXR (1)

Cell wall (1)

VDA (1)

OCT (1)

N-Acetylglucosaminyltransferase (1)

Stemness kinase (1)

RANKL/RANK (1)

Annexin A (1)

Adiponectin receptor (1)

Fas/FasL (1)

FABP (1)

Anion Exchanger (1)

Thioredoxin (1)

PGC-1α (1)

Somatostatin (1)

Glutathione reductase (1)

GPCR19 (1)

CPT (1)

GluCls (1)

TSH Receptor (1)

HuR (1)

Fer/FerT kinase (1)

lysosomal autophagy (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
{{item.packagingtext}}