Nuclear Receptor Compound Library

Product No.： L1510

Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease.

TargetMol collects 531 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.

Product No.：L1510

Product Description

A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
Bioactivity and safety confirmed by pre-clinical research and clinical trials;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

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Compound library Consultation

Composition of compound library

PPAR (121)

Estrogen/progestogen Receptor (94)

Estrogen Receptor/ERR (84)

Autophagy (68)

Androgen Receptor (64)

Glucocorticoid Receptor (62)

Endogenous Metabolite (49)

Others (46)

Retinoid Receptor (39)

Apoptosis (31)

ROR (22)

Thyroid hormone receptor(THR) (21)

Progesterone Receptor (21)

FXR (21)

AhR (20)

Antibacterial (16)

Liver X Receptor (15)

COX (15)

Aryl Hydrocarbon Receptor (10)

P450 (10)

NF-κB (9)

Ferroptosis (8)

Reactive Oxygen Species (7)

Antifungal (6)

GPR (6)

RAR/RXR (5)

Drug Metabolite (5)

Akt (5)

AMPK (5)

Potassium Channel (5)

Mitophagy (4)

Parasite (4)

Adrenergic Receptor (4)

Annexin A (4)

MMP (4)

Prostaglandin Receptor (4)

TSH Receptor (4)

Influenza Virus (4)

Antibiotic (4)

Reductase (3)

JNK (3)

TRP/TRPV Channel (3)

IL Receptor (3)

Lipoxygenase (3)

GPCR19 (3)

Tyrosinase (3)

HIV Protease (2)

p38 MAPK (2)

Glutathione Peroxidase (2)

Phosphatase (2)

Virus Protease (2)

PARP (2)

VEGFR (2)

PKC (2)

PDE (2)

ROS (2)

Smo (2)

BCL (2)

Interleukin (2)

SARS-CoV (2)

Sirtuin (2)

transporter (2)

Nrf2 (2)

Aromatase (2)

GABA Receptor (2)

TNF (2)

Cannabinoid Receptor (2)

AChR (2)

p53 (2)

NO Synthase (2)

Proteasome (1)

Adenylyl cyclase (1)

NOS (1)

Carbonic Anhydrase (1)

Histone Methyltransferase (1)

HCV Protease (1)

Ligands for Target Protein for PROTAC (1)

Dehydrogenase (1)

c-Met/HGFR (1)

Antioxidant (1)

GSK-3 (1)

Melatonin Receptor (1)

ABC (1)

MRP (1)

PKA (1)

HBV (1)

Wnt/beta-catenin (1)

Cysteine Protease (1)

Leukotriene Receptor (1)

Glucokinase (1)

Caspase (1)

Calcium Channel (1)

ERK (1)

MAO (1)

FLAP (1)

LDL (1)

Gamma-secretase (1)

Phosphorylase (1)

Glucosidase (1)

Antifection (1)

Opioid Receptor (1)

PAK (1)

Epoxide Hydrolase (1)

GluR (1)

Epigenetic Reader Domain (1)

CaMK (1)

EGFR (1)

DNA/RNA Synthesis (1)

STAT (1)

Ligand for E3 Ligase (1)

Phospholipase (1)

Complement System (1)

FLT (1)

c-Kit (1)

Sodium Channel (1)

DNA Methyltransferase (1)

TAM Receptor (1)

Thrombin (1)

HIF/HIF Prolyl-Hydroxylase (1)

HER (1)

S1P Receptor (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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