Drug activity screening is a step in the modern drug development process that involves testing and identifying compounds with specific physiological activities. It refers to the process of selecting compounds with high activity against a specific target through standardized experimental methods from a large number of compounds or new compounds. It is a new technical system formed by the organic integration of various technological methods.

Drug activity screening technologies are based on molecular and cellular-level experimental methods, utilizing microplates as the experimental tool carrier. The process involves the execution of experimental procedures by an automated operating system, the collection of experimental data by sensitive and rapid detection instruments, and the analysis and processing of the obtained data by a computer. Currently, target-based drug activity screening is widely applied in the discovery of various drugs and is an essential step in the development of clinical new drugs.