Screening of Antitumor Drugs in Vitro

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Customers only need to provide compounds of the target to be tested, each 2-3mg, we will arrange the corresponding screening and testing services, and finally provide professional detection and analysis reports.

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Thank you for choosing our in vitro screening and analysis services for anti-tumor drugs. If you have any relevant questions, please contact our staff, we will answer and serve you immediately.

Introduction to in Vitro Screening of Antitumor Drugs

In vitro drug screening is currently the most common in vitro anti-tumor drug testing, we have more than 110 STR identified human tumor cells library, to provide our customers with a variety of compounds preliminary screening. In addition to the direct screening of enzymatic targets, it is also possible to detect and evaluate the effects of compounds on cells as a whole when the specific targets of drugs are unknown, so as to screen out more effective and safe drugs.

Drug screen has many years of experience in drug screening, can provide customers with a variety of high-end quality services, and can design and plan experimental programs according to customers' specific needs, to provide customers with perfect solutions to help you quickly find compounds with development potential in the early stage of drug research and development.

Human Tumor Cell Model

Species	Human Tumor Cells
Glioma	A172、U-118 MG、U-87 MG、U251
Oral, Nasopharyngeal and Throat Cancer	KB、Tca-8113、CAL 27、CNE、FaDu、HEp-2
Thyroid Gland	SW579、TT
Oesophageal Cancer	Eca-109、TE-1
Breast Cancer	ZR-75-1、SK-BR-3、MDA-MB-468、MDA-MB-453、MDA-MB-231、MCF-7、BT-474、T-47D、BT-549、 MDA-MB-435、Hs 578T
Gastric Cancer	SNU-1、NCI-N87、KATO III、BGC-823、HGC-27、AGS
Liver Cancer	Hep G2、Hep 3B2.1-7、HCCC-9810、HuH-7、QGY-7701、RBE、HuH-6
Lung Cancer	NCI-H460、NCI-H358、NCI-H1650、NCI-H1299、NCI-H292、HCC827、A549、SK-MES-1、 Calu-6、NCI-H1975、95-D、NCI-H226、SPC-A-1、Calu-3
Carcinoma of Gallbladder	GBC-SD
Pancreatic Cancer	SW 1990、PANC-1、CFPAC-1、BxPC-3、AsPC-1
Prostate Cancer	PC-3、PC-3M、DU 145、22RV1
Renal Cancer	SK-NEP-1、Caki-1、786-O(786-0)、OS-RC-2、769-P
Ovarian Cancer	SK-OV-3、OVCAR-3、HO-8910
Cervical Cancer	C-33 A、MS751、SiHa、Ca Ski、HeLa、HCC 94、Ishikawa、ME-180
Endometrial Adenocarcinoma	RL95-2、HEC-1-A、HEC-1-B、C-33 A、MS751、SiHa、Ca Ski、HeLa、HCC 94、Ishikawa、ME-180
Carcinoma of Bladder	5637、UM-UC-3、SW 780、J82、T24、EJ-1、RT4
Colon Cancer	SW620、LoVo、HT-29、HCT 116、COLO 205、RKO-E6、SW1116、RKO、LS 174T、Caco-2、 SW480 [SW-480]、DLD-1、HCT-15
Osteosarcoma	Saos-2、U-2 OS、MG-63、SW 1353
Neuroblastoma	SK-N-SH、SK-N-BE(2)、SH-SY5Y[SHSY-5Y]
lymphoma	CA46、Raji、NAMALWA、RAMOS、U-937、Daudi
Skin Cancer, Melanoma	A-431、A-375、C918
leukaemia	HuT 78、6T-CEM、Jurkat, Clone E6-1、KG-1、CCRF-CEM、CEM/C1、HL-60、K-562、THP-1、A3、HEL
Other	RD、JAR、JEG-3、HT-1080、Acc-2、etc.

The CCK8 experiment

WST is reduced by the electron carrier 1-methoxy-5-methylphenazine dimethyl sulfate (1-Methoxy PMS) to the highly water-soluble yellow Formazan dye by the cell dehydrogenase.
The amount of substance produced is proportional to the number of living cells. Therefore, CCK8 experiment is to use this property to directly analyze cell proliferation and toxicity.

Cell Titer-Glo Detection

Normal living cells rely on ATP to supply energy for various life activities, and the ATP released is positively correlated with the number of living cells.
The use of luciferase to catalyze the substrate to produce biological cold light requires the participation of ATP, and the content of ATP generated by Cell lysis can be judged by the strength of the luminous signal. Therefore, cell Titer-Glo detection is used to indirectly obtain cell vitality data.

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