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Nuclear Receptor Target Screening

Sample Delivery
Customers only need to provide compounds of the target to be tested, each 2-3mg, we will arrange the corresponding screening and testing services, and finally provide professional detection and analysis reports.
Inquiry and Order
Thank you for choosing our ion channel target drug screening and analysis services. If you have any relevant questions, please contact our staff, we will answer and serve you immediately.
Introduction to Nuclear Receptor Target Screening

The nuclear receptor superfamily includes many transcription factors that play important regulatory roles in the development and homeostasis of multicellular organisms. In addition to their normal physiological functions, nuclear receptors are involved in many pathological processes, and the importance of these transcriptional regulations in biomedical research cannot be underestimated.

Drug Screen can provide customers with high-quality comprehensive nuclear receptor screening services, available in both 96-well and 384-well plate screening modes to accelerate your drug development process.

Nuclear Receptor Target Screening Model

Target Assay Format
Androgen Receptor TR-FRET/Cell based 96/384
Aryl Hydrocarbon Receptor Cell based 96/384
Constitutive Androstane Receptor isoform 1/3 TR-FRET/Cell based 96/384
ER alpha/beta TR-FRET/Cell based 96/384
ERR (estrogen related receptor) alpha/beta/gamma TR-FRET/Cell based 96/384
FXR (farnesoid X receptor) TR-FRET 96/384
Glucocorticoid Receptor (GR) Glucocorticoid Receptor (GR) 96/384
Liver Receptor Homolog-1 Cell based 96/384
LXR (liver X receptor) alpha/beta TR-FRET/Cell based 96/384
Mineralocorticoid Receptor (MR) Cell based 96/384
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) Cell based 96/384
PPAR alpha/delta/gamma TR-FRET/Cell based 96/384
Pregnane X Receptor Cell based 96/384
Progesterone Receptor TR-FRET/Cell based 96/384
RAR-related orphan receptor gamma (RORγ) Cell based 96/384
Retinoic Acid Receptor (RAR) alpha/beta/gamma TR-FRET/Cell based 96/384
Retinoid X Receptor (RXR) alpha/beta/gamma TR-FRET/Cell based 96/384
TR(thyroid receptor) alpha/beta TR-FRET/Cell based 96/384
TR-FRET LXR(liver X receptor)beta TR-FRET 96/384
Vitamin D Receptor(VDR) TR-FRET/Cell based 96/384

Main Detection Method

At present, nuclear receptor screening models can provide two detection methods at cell level and protein level: cytological method is reporter gene detection method; The non-cellular test is TR-FRET.

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Basic Information
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Note: The exact values need to be tested, and the predicted values are predicted
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