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toxic_compound_library
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Toxic Compound Library
Product No.: L5500

TargetMol’s Toxic Compound Library include 262 synthetic and natural toxic substances that can alter cellular, metabolic and membrane functions, such as DNA/ RNA synthesis inhibitors, cytotoxic agents, immune suppressants, anti-proliferatives, endocrine disruptors and other agents. This special collection finds application in testing the sensitivity, development and profiling of new assays in high throughput screening (HTS) programs used in new drug discovery.

Product No.:L5500
  • A unique collection of 262 toxic substances for high throughput screening (HTS) and high content screening (HCS);
  • Covers more than 150 targets related to immune diseases, neurological diseases, respiratory disorders, endocrine diseases, and cardiovascular diseases.
  • Includes 222 drugs with certain studies on mechanisms of toxicity;
  • Includes 89 natural products, most of which are effective ingredients of Chinese medicine and attractive for toxicological study.
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
Compound Service
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Composition of compound library
DNA/RNA Synthesis (67)
Apoptosis (58)
Autophagy (55)
Antibacterial (46)
Antibiotic (44)
Others (42)
Endogenous Metabolite (28)
Parasite (21)
Nucleoside Antimetabolite/Analog (19)
COX (12)
Dehydrogenase (11)
Antifungal (11)
Topoisomerase (11)
Potassium Channel (11)
DNA Alkylator/Crosslinker (10)
Histamine Receptor (10)
Mitophagy (10)
HSV (9)
Reactive Oxygen Species (8)
HIV Protease (7)
SARS-CoV (7)
AChR (7)
Ferroptosis (6)
Adrenergic Receptor (6)
ribosome (6)
Microtubule Associated (6)
Dopamine Receptor (5)
PPAR (5)
PDE (5)
Influenza Virus (5)
5-HT Receptor (5)
HCV Protease (4)
Antifolate (4)
Calcium Channel (4)
Antifection (4)
BCL (4)
DNA Alkylation (4)
DNA (4)
STAT (4)
Sodium Channel (4)
ATPase (3)
Antioxidant (3)
Virus Protease (3)
HBV (3)
PKC (3)
MAO (3)
NMDAR (3)
mTOR (3)
EGFR (3)
HDAC (3)
NF-κB (3)
Phospholipase (3)
P450 (3)
Thyroid hormone receptor(THR) (2)
Chloride channel (2)
CAT (2)
Transferase (2)
DHFR (2)
Adenosine Receptor (2)
Phosphatase (2)
PKA (2)
Wnt/beta-catenin (2)
Glucocorticoid Receptor (2)
iGluR (2)
Drug Metabolite (2)
Mitochondrial Metabolism (2)
ROS (2)
Opioid Receptor (2)
Lipoxygenase (2)
Norepinephrine (2)
Akt (2)
AChE (2)
HSP (2)
TLR (2)
Casein Kinase (2)
Aromatase (2)
AMPK (2)
TNF (2)
DNA Methyltransferase (2)
Tyrosinase (2)
Monoamine Oxidase (2)
Proteasome (1)
Proton pump (1)
Carbonic Anhydrase (1)
ROR (1)
Amino Acids and Derivatives (1)
p38 MAPK (1)
PI3K (1)
c-Met/HGFR (1)
Cell wall (1)
NADPH (1)
Glutathione Peroxidase (1)
Factor Xa (1)
Tyrosine Kinases (1)
Rho (1)
Serotonin Transporter (1)
VEGFR (1)
TRP/TRPV Channel (1)
ERK (1)
Adiponectin receptor (1)
UGT (1)
MTH1 (1)
Gamma-secretase (1)
CDK (1)
DNA gyrase (1)
PAK (1)
Hedgehog/Smoothened (1)
CXCR (1)
Endothelin Receptor (1)
MMP (1)
PAD (1)
GluR (1)
IGF-1R (1)
DUB (1)
TGF-beta/Smad (1)
P-gp (1)
Prostaglandin Receptor (1)
Trk receptor (1)
Sirtuin (1)
Nrf2 (1)
RSV (1)
IκB/IKK (1)
Reverse Transcriptase (1)
Retinoid Receptor (1)
KLF (1)
CRISPR/Cas9 (1)
GPR (1)
GABA Receptor (1)
HIF (1)
Adenosine deaminase (1)
MEK (1)
FGFR (1)
Complement System (1)
Syk (1)
HMG-CoA Reductase (1)
Ras (1)
Sigma receptor (1)
HIF/HIF Prolyl-Hydroxylase (1)
AhR (1)
CFTR (1)
p53 (1)
NO Synthase (1)
HER (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE