RO5 Drug-like Natural Product Library

Product No.： L6160

Natural products are important sources of lead compounds and drug candidates. They have complex scaffold structures and rich functional groups. Their structures are unique, and most of them are chiral. These naturally occurring advantages provide more diverse options for the transformation of natural products into drugs, and are also the reasons why natural products play an important role in drug development and research.

Based on the structural diversity and novelty of natural products, TargetMol used the druglikeness prediction index "Lipinski's Rule of Five" to select 2703 natural product monomers with good druggabilities, covering diverse structures from vast sources such as terpenes and alkaloids. The library is consisted of monomers with both biological activity and drug-like properties. It is a powerful tool for subsequent structure-effect optimization and innovative drug research.

Product No.：L6160

Product Description

2703 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery.
Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more.
Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories.
Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives.

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

Autophagy (168)

NF-κB (112)

Antifungal (101)

Antibiotic (81)

Reactive Oxygen Species (73)

Parasite (66)

Antioxidant (61)

COX (60)

P450 (50)

AChR (46)

Influenza Virus (43)

Anti-infection (42)

DNA/RNA Synthesis (40)

AChE (38)

TNF (37)

p38 MAPK (35)

GABA Receptor (33)

IL Receptor (32)

Caspase (31)

ERK (31)

Tyrosinase (31)

Calcium Channel (30)

HIV Protease (29)

Akt (29)

5-HT Receptor (29)

Ferroptosis (28)

STAT (28)

NO Synthase (28)

Estrogen/progestogen Receptor (27)

Adrenergic Receptor (26)

Topoisomerase (26)

Virus Protease (24)

AMPK (24)

TRP/TRPV Channel (22)

Nrf2 (22)

PI3K (21)

PPAR (21)

MMP (21)

Estrogen Receptor/ERR (20)

ROS (20)

Lipoxygenase (20)

NOS (19)

Dopamine Receptor (19)

BCL (19)

PDE (18)

Antifection (18)

PKC (17)

Potassium Channel (17)

Dehydrogenase (16)

JNK (16)

PARP (16)

Microtubule Associated (16)

Nucleoside Antimetabolite/Analog (15)

HSV (15)

EGFR (15)

Mitophagy (14)

Adenosine Receptor (13)

Histamine Receptor (13)

iGluR (13)

Drug Metabolite (13)

Prostaglandin Receptor (13)

HDAC (13)

Amino Acids and Derivatives (12)

Glucosidase (12)

Mitochondrial Metabolism (12)

Antiviral (12)

Sodium Channel (12)

Wnt/beta-catenin (11)

VEGFR (11)

MAO (11)

GluR (11)

Androgen Receptor (11)

P-gp (11)

HIF/HIF Prolyl-Hydroxylase (11)

ATPase (10)

Immunology/Inflammation related (10)

Glucocorticoid Receptor (10)

NMDAR (10)

JAK (10)

HBV (9)

CDK (9)

SARS-CoV (9)

Monoamine Oxidase (9)

Opioid Receptor (8)

Sirtuin (8)

HCV Protease (7)

Progesterone Receptor (7)

TGF-beta/Smad (7)

TLR (7)

Phospholipase (7)

NOD (7)

Chloride channel (6)

PKA (6)

Fatty Acid Synthase (6)

mTOR (6)

Indoleamine 2,3-Dioxygenase (IDO) (6)

Interleukin (6)

MAPK (6)

IκB/IKK (6)

Beta Amyloid (6)

GPR (6)

HIF (6)

HMG-CoA Reductase (6)

Carbonic Anhydrase (5)

Transferase (5)

Src (5)

Reductase (5)

BACE (5)

NADPH (5)

Phosphatase (5)

FXR (5)

Aryl Hydrocarbon Receptor (5)

PAFR (5)

Gamma-secretase (5)

Xanthine Oxidase (5)

transporter (5)

Reverse Transcriptase (5)

Cannabinoid Receptor (5)

Platelet aggregation (5)

AhR (5)

HER (5)

Arginase (4)

c-Met/HGFR (4)

Serine/threonin kinase (4)

UGT (4)

LDL (4)

cAMP (4)

ATP Citrate Lyase (4)

PGE Synthase (4)

HSP (4)

MEK (4)

FGFR (4)

Syk (4)

DNA Methyltransferase (4)

p53 (4)

Thyroid hormone receptor(THR) (3)

Proton pump (3)

DHFR (3)

ROR (3)

Integrin (3)

Glutathione Peroxidase (3)

GSK-3 (3)

MRP (3)

Tyrosine Kinases (3)

Serotonin Transporter (3)

IAP (3)

Hedgehog/Smoothened (3)

CCR (3)

Epigenetic Reader Domain (3)

CaMK (3)

Telomerase (3)

Lipid (3)

Beta-Secretase (3)

Trk receptor (3)

Free radical scavengers (3)

GPCR19 (3)

GST (3)

ribosome (3)

Aromatase (3)

FAK (3)

Imidazoline Receptor (3)

Proteasome (2)

LTR (2)

DYRK (2)

RAAS (2)

gp120/CD4 (2)

c-Myc (2)

Serine Protease (2)

Cysteine Protease (2)

RANKL/RANK (2)

Amylase (2)

E1/E2/E3 Enzyme (2)

Phosphorylase (2)

DNA gyrase (2)

Smo (2)

DPP-4 (2)

PDGFR (2)

PAK (2)

FAAH (2)

CXCR (2)

Aurora Kinase (2)

IGF-1R (2)

DNA (2)

OAT (2)

Aminopeptidase (2)

Decarboxylase (2)

PAI-1 (2)

Casein Kinase (2)

ATM/ATR (2)

PDK (2)

Ras (2)

Thrombin (2)

NOD-like Receptor (NLR) (2)

PKM (2)

advanced glycation end products (1)

Mdm2 (1)

Adenylyl cyclase (1)

CAT (1)

Transaminase (1)

Monocarboxylate transporter (1)

Hydrogenase (1)

CD38 (1)

CYP19A1 (1)

LPL Receptor (1)

DNA Alkylator/Crosslinker (1)

P2Y Receptor (1)

aconitase (1)

RAR/RXR (1)

Factor Xa (1)

Melatonin Receptor (1)

OCT (1)

ABC (1)

Pim (1)

Antifolate (1)

Liver X Receptor (1)

Leukotriene Receptor (1)

IDO (1)

Prolyl Endopeptidase (PREP) (1)

IRE1 (1)

Adiponectin receptor (1)

Raf (1)

MT Receptor (1)

P2X Receptor (1)

GlyT (1)

Hexokinase (1)

Monoamine Transporter (1)

Stearoyl-CoA Desaturase (SCD) (1)

Somatostatin (1)

PAD (1)

Norepinephrine (1)

SGLT (1)

BCRP (1)

Acyltransferase (1)

Histone Acetyltransferase (1)

hCE (1)

Pyroptosis (1)

ALK (1)

Carboxypeptidase (1)

Retinoid Receptor (1)

CRISPR/Cas9 (1)

Hydroxylase (1)

PLK (1)

ATTECs (1)

Neurokinin receptor (1)

NMU2R (1)

FLT (1)

NADPH-oxidase (1)

IRAK (1)

S6 Kinase (1)

ROS Kinase (1)

CFTR (1)

PD-1/PD-L1 (1)

S1P Receptor (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
{{item.packagingtext}}