PPI Inhibitor Library

Product No.： L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy.

TargetMol’s PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

Product No.：L9400

Product Description

A unique collection of 485 PPI-related compounds for drug screening;
Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
Detailed compound information with structure, target, and biological activity description;
NMR and HPLC validated to ensure high purity and quality.

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

Epigenetic Reader Domain (111)

Others (83)

Apoptosis (77)

BCL (71)

Autophagy (37)

Nrf2 (33)

p53 (25)

HIV Protease (23)

Mdm2 (21)

E1/E2/E3 Enzyme (20)

Histone Methyltransferase (16)

Caspase (15)

PD-1/PD-L1 (14)

IAP (13)

NF-κB (12)

Ferroptosis (11)

Endogenous Metabolite (11)

RIP kinase (10)

Wnt/beta-catenin (9)

DNA/RNA Synthesis (9)

Ras (9)

PARP (8)

Histone Acetyltransferase (8)

p38 MAPK (7)

Microtubule Associated (7)

c-Myc (6)

COX (6)

Sirtuin (6)

STAT (6)

Parasite (5)

Rho (5)

CDK (5)

Raf (5)

Antibacterial (5)

Akt (5)

TNF (5)

PROTACs (4)

Integrin (4)

Dehydrogenase (4)

JNK (4)

ERK (4)

IL Receptor (4)

Ligand for E3 Ligase (4)

Ligands for Target Protein for PROTAC (3)

YAP (3)

PI3K (3)

PERK (3)

Mitophagy (3)

PPAR (3)

PKC (3)

NMDAR (3)

Reactive Oxygen Species (3)

CXCR (3)

mTOR (3)

P-gp (3)

HSP (3)

HIF (3)

Sodium Channel (3)

HIF/HIF Prolyl-Hydroxylase (3)

Dopamine Receptor (2)

DNA-PK (2)

Src (2)

NEDD8 (2)

Estrogen/progestogen Receptor (2)

Antifungal (2)

Antioxidant (2)

DNA Alkylator/Crosslinker (2)

IFNAR (2)

GTPase (2)

Phosphatase (2)

GSK-3 (2)

Virus Protease (2)

Calcium Channel (2)

Aryl Hydrocarbon Receptor (2)

iGluR (2)

PDE (2)

Integrase (2)

JAK (2)

Lipoxygenase (2)

Influenza Virus (2)

IκB/IKK (2)

Carboxypeptidase (2)

Reverse Transcriptase (2)

HDAC (2)

GABA Receptor (2)

5-HT Receptor (2)

PLK (2)

Antibiotic (2)

Chloride channel (1)

ATPase (1)

Proton pump (1)

NPC1L1 (1)

HCV Protease (1)

MyD88 (1)

NADPH (1)

RAAS (1)

Histamine Receptor (1)

Glutathione Peroxidase (1)

Estrogen Receptor/ERR (1)

Serotonin Transporter (1)

Serine/threonin kinase (1)

Cysteine Protease (1)

Liver X Receptor (1)

FXR (1)

Neurotensin Receptor (1)

Glucokinase (1)

VEGFR (1)

MAO (1)

Topoisomerase (1)

Myosin (1)

UGT (1)

Gamma-secretase (1)

Mitochondrial Metabolism (1)

Monoamine Transporter (1)

ROS (1)

Molecular Glues (1)

Smo (1)

Hedgehog/Smoothened (1)

CCR (1)

MMP (1)

GluR (1)

IGF-1R (1)

DNA (1)

Androgen Receptor (1)

Interleukin (1)

TGF-beta/Smad (1)

AChE (1)

MNK (1)

Prostaglandin Receptor (1)

TLR (1)

STING (1)

SARS-CoV (1)

GPCR19 (1)

Ephrin Receptor (1)

transporter (1)

HuR (1)

Beta Amyloid (1)

Retinoid Receptor (1)

PDK (1)

P450 (1)

Potassium Channel (1)

ATTECs (1)

Neurokinin receptor (1)

Discoidin Domain Receptor (DDR) (1)

Anti-infection (1)

DNA Methyltransferase (1)

HMG-CoA Reductase (1)

Tyrosinase (1)

Thrombin (1)

FAK (1)

AhR (1)

MLK (1)

Monoamine Oxidase (1)

NO Synthase (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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