Human Endogenous Metabolite Library

Product No.： L2500

Human endogenous metabolites, which are produced and found within the human body, primarily include carbohydrates, bioactive peptides, nucleosides and nucleic acids, endogenous regulatory factors, cytokines, and proteins. These metabolites are often involved in essential physiological processes in the body, exerting specific physiological functions and biological activities.

Human endogenous metabolites can serve as diagnostic biomarkers. For instance, in the field of cancer research, methods for malignant tumors diagnose, drug screening, and drug toxicity assessment based on the abnormal changes in characteristic small-molecule metabolic biomarkers inside and outside tumor cells have become a hotspot for research. In addition to their role as biomarkers, human endogenous metabolites also play crucial physiological roles. Numerous research results confirms that there is a close relationship between many diseases and the alterations in endogenous substances. Therefore, investigating endogenously active compounds as a starting point for finding drugs to treat diseases has become one of the primary approaches in drug research.

The TargetMol’s Human Endogenous Metabolite Library consists of a selection of 499 human endogenous metabolites, serving as effective tools for exploring the disease mechanisms and discovering new drugs.

Product No.：L2500

Product Description

A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
Some products are already approved or in clinical phase, indicating both biological safety and significant biological activity.
Diverse categories, including carboxylic acids, amino acids, biogenic amines, polyamines, nucleotides, coenzymes, vitamins, carbohydrates, fatty acids, lipids, steroids, hormones and various other metabolism-related compounds.
Detailed information, including molecular formula, molecular weight, SMILES, product descriptions, compound categories, cellular distribution, biological sample distribution, tissue distribution, related diseases, and references.
Utilization of various detection techniques such as NMR, HPLC, and LCMS to ensure accurate compound structures and high purity, and reduces false positives.

Compound Service

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Compound library Consultation

Composition of compound library

Apoptosis (18)

Autophagy (17)

Antibacterial (16)

Amino Acids and Derivatives (9)

Estrogen/progestogen Receptor (9)

Nucleoside Antimetabolite/Analog (9)

DNA/RNA Synthesis (9)

iGluR (6)

Reactive Oxygen Species (6)

GluR (6)

Ferroptosis (5)

Antifungal (5)

NMDAR (5)

Influenza Virus (5)

5-HT Receptor (5)

NO Synthase (5)

Antioxidant (4)

Adenosine Receptor (4)

Thyroid hormone receptor(THR) (3)

Arginase (3)

Dehydrogenase (3)

Mitophagy (3)

Phosphatase (3)

Estrogen Receptor/ERR (3)

PPAR (3)

FXR (3)

Glucocorticoid Receptor (3)

GABA Receptor (3)

Cannabinoid Receptor (3)

AhR (3)

Chloride channel (2)

ATPase (2)

Transferase (2)

Dopamine Receptor (2)

Reductase (2)

Progesterone Receptor (2)

Caspase (2)

PKC (2)

TRP/TRPV Channel (2)

Aryl Hydrocarbon Receptor (2)

ROS (2)

HSV (2)

MMP (2)

Prostaglandin Receptor (2)

GPCR19 (2)

AMPK (2)

TNF (2)

Potassium Channel (2)

AChR (2)

Anti-infection (2)

NOD (2)

HMG-CoA Reductase (2)

Antibiotic (2)

Imidazoline Receptor (2)

HIV Protease (1)

Carbonic Anhydrase (1)

DHFR (1)

ROR (1)

p38 MAPK (1)

P2Y Receptor (1)

NADPH (1)

Histamine Receptor (1)

Glutathione Peroxidase (1)

Virus Protease (1)

Melatonin Receptor (1)

MRP (1)

PKA (1)

Wnt/beta-catenin (1)

PARP (1)

Cysteine Protease (1)

Liver X Receptor (1)

Calcium Channel (1)

ERK (1)

Adrenergic Receptor (1)

MAO (1)

LDL (1)

Drug Metabolite (1)

MT Receptor (1)

P2X Receptor (1)

GlyT (1)

Mitochondrial Metabolism (1)

Antifection (1)

Opioid Receptor (1)

Fatty Acid Synthase (1)

IL Receptor (1)

Bradykinin Receptor (1)

Somatostatin (1)

Xanthine Oxidase (1)

CaMK (1)

mTOR (1)

Androgen Receptor (1)

Akt (1)

Glutathione reductase (1)

AChE (1)

HSP (1)

Trk receptor (1)

Decarboxylase (1)

Nrf2 (1)

Beta Amyloid (1)

Reverse Transcriptase (1)

NF-κB (1)

Oxytocin Receptor (1)

P450 (1)

HIF (1)

FGFR (1)

Neurokinin receptor (1)

DNA Methyltransferase (1)

Microtubule Associated (1)

Tyrosinase (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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