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hematonosis_compound_library
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Hematonosis Compound Library
Product No.: L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases.

Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

Product No.:L8400
  • A unique collection of 514 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;
Compound Service
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Compound library Consultation
Composition of compound library
Apoptosis (153)
Autophagy (101)
Others (59)
PI3K (32)
DNA/RNA Synthesis (29)
Bcr-Abl (24)
Endogenous Metabolite (23)
HDAC (23)
FLT (23)
CDK (22)
Topoisomerase (21)
Histone Methyltransferase (18)
Antibacterial (17)
c-Kit (17)
Dehydrogenase (16)
ALK (16)
Src (15)
JAK (14)
PDGFR (14)
mTOR (14)
Nucleoside Antimetabolite/Analog (13)
VEGFR (12)
HIV Protease (11)
Epigenetic Reader Domain (10)
FGFR (10)
TAM Receptor (10)
Antibiotic (10)
PKC (9)
E1/E2/E3 Enzyme (9)
BCL (9)
Microtubule Associated (9)
Proteasome (8)
c-Met/HGFR (8)
Mitophagy (8)
Tyrosine Kinases (8)
Aurora Kinase (8)
Influenza Virus (8)
AMPK (8)
DNA Alkylator/Crosslinker (7)
GSK-3 (7)
BTK (7)
Trk receptor (7)
NF-κB (7)
PLK (7)
c-RET (7)
COX (6)
HSP (6)
STAT (6)
Ligand for E3 Ligase (6)
Antifungal (5)
Antifolate (5)
Caspase (5)
ROS (5)
Isocitrate Dehydrogenase (IDH) (5)
Reactive Oxygen Species (5)
Akt (5)
Retinoid Receptor (5)
c-Fms (5)
TNF (5)
Syk (5)
Mdm2 (4)
DNA-PK (4)
Histone Demethylase (4)
Virus Protease (4)
Parasite (4)
ERK (4)
Raf (4)
DNA Alkylation (4)
Chk (4)
IGF-1R (4)
MEK (4)
AChR (4)
Ras (4)
ROS Kinase (4)
PROTACs (3)
Transferase (3)
Ligands for Target Protein for PROTAC (3)
Ferroptosis (3)
Adenosine Receptor (3)
HBV (3)
Wnt/beta-catenin (3)
Pim (3)
Rho (3)
IAP (3)
CSF-1R (3)
Gamma-secretase (3)
Mitochondrial Metabolism (3)
Molecular Glues (3)
Smo (3)
Hedgehog/Smoothened (3)
IL Receptor (3)
DUB (3)
Aminopeptidase (3)
Sirtuin (3)
Nrf2 (3)
ATM/ATR (3)
Potassium Channel (3)
DNA Methyltransferase (3)
IRAK (3)
S6 Kinase (3)
HIF/HIF Prolyl-Hydroxylase (3)
p53 (3)
NEDD8 (2)
p38 MAPK (2)
TOPK (2)
Phosphatase (2)
PKA (2)
Liver X Receptor (2)
NAMPT (2)
IRE1 (2)
HSV (2)
MMP (2)
KSP (2)
CaMK (2)
Androgen Receptor (2)
Interleukin (2)
EGFR (2)
MAPK (2)
P-gp (2)
Antiviral (2)
SARS-CoV (2)
Histone Acetyltransferase (2)
transporter (2)
Casein Kinase (2)
IκB/IKK (2)
Phospholipase (2)
GABA Receptor (2)
Adenosine deaminase (2)
Sodium Channel (2)
BMI-1 (2)
Thrombin (2)
FAK (2)
Kinesin (2)
Chloride channel (1)
ATPase (1)
Monocarboxylate transporter (1)
DHFR (1)
MALT (1)
Dopamine Receptor (1)
HCV Protease (1)
Integrin (1)
CRM1 (1)
Amino Acids and Derivatives (1)
Estrogen/progestogen Receptor (1)
YAP (1)
LTR (1)
DYRK (1)
NADPH (1)
Histamine Receptor (1)
JNK (1)
Tie-2 (1)
GTPase (1)
c-Myc (1)
PPAR (1)
Serine Protease (1)
Hck (1)
Serine/threonin kinase (1)
Cysteine Protease (1)
Glutaminase (1)
Adrenergic Receptor (1)
Immunology/Inflammation related (1)
Haspin Kinase (1)
Drug Metabolite (1)
NMDAR (1)
DNA gyrase (1)
Antifection (1)
Monoamine Transporter (1)
DPP-4 (1)
Fatty Acid Synthase (1)
PAK (1)
CXCR (1)
PAD (1)
ACK (1)
GluR (1)
Lipoxygenase (1)
TGF-beta/Smad (1)
SGLT (1)
Lipid (1)
Wee1 (1)
OXPHOS (1)
BCRP (1)
Survivin (1)
MNK (1)
TLR (1)
Ephrin Receptor (1)
MELK (1)
Methionine Adenosyltransferase (MAT) (1)
Hippo pathway (1)
Reverse Transcriptase (1)
Aromatase (1)
KLF (1)
GPR (1)
P450 (1)
HIF (1)
Anti-infection (1)
p97 (1)
MLK (1)
PD-1/PD-L1 (1)
S1P Receptor (1)
NO Synthase (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE