Endocrine glands are made of a group of cells that secrete their products, hormones, directly into the blood rather than through a duct. Hormones are transported by the circulatory system to target distant organs to regulate physiology and behavior, such as metabolism, growth, development, and reproduction. Hormones have diverse chemical structures, mainly of 3 classes: eicosanoids, steroids, and amino acid/protein derivatives. Endocrine disease is characterized by irregulated hormone release, inappropriate response to signaling, lack of a gland, or structural enlargement in a critical site such as the thyroid.

The Endocrinology-Hormones Compound Library by TargetMol, containing 784 compounds targeting endocrine system, can be used for research in endocrine system, high throughput screening and high content screening for new drugs in endocrine diseases.