DNA Damage & Repair Compound Library

Product No.： L3900

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol’s DNA Damage & Repair Compound Library, a unique collection of 910 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

Product No.：L3900

Product Description

A unique collection of 910 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

Apoptosis (141)

PPAR (123)

HDAC (112)

Autophagy (106)

Topoisomerase (98)

Others (80)

PARP (77)

Antibacterial (75)

Antibiotic (64)

Nucleoside Antimetabolite/Analog (63)

Sirtuin (55)

Endogenous Metabolite (52)

DNA-PK (38)

DUB (34)

PI3K (31)

ATM/ATR (24)

DNA Alkylator/Crosslinker (21)

Influenza Virus (20)

HIV Protease (19)

Parasite (19)

mTOR (19)

HSV (16)

Dehydrogenase (15)

DNA Alkylation (15)

DNA (15)

COX (15)

NF-κB (15)

DHFR (14)

DNA gyrase (14)

Telomerase (13)

Caspase (12)

Reactive Oxygen Species (12)

Mitophagy (11)

Wnt/beta-catenin (10)

Antifolate (10)

Antifungal (9)

BCL (9)

SARS-CoV (9)

Potassium Channel (9)

p38 MAPK (8)

Ferroptosis (8)

Virus Protease (8)

PDE (8)

P450 (8)

p53 (8)

HCV Protease (7)

HBV (7)

AMPK (7)

Antifection (6)

IL Receptor (6)

CRISPR/Cas9 (6)

PKC (5)

MTH1 (5)

Epigenetic Reader Domain (5)

Akt (5)

TNF (5)

Reverse Transcriptase (5)

GABA Receptor (5)

BMI-1 (5)

Tyrosinase (5)

Adenosine Receptor (4)

PKA (4)

Bcr-Abl (4)

CDK (4)

Drug Metabolite (4)

Lipoxygenase (4)

TGF-beta/Smad (4)

Prostaglandin Receptor (4)

Nrf2 (4)

AChR (4)

DNA Methyltransferase (4)

Carbonic Anhydrase (3)

ATPase (3)

Calcium Channel (3)

TRP/TRPV Channel (3)

Mitochondrial Metabolism (3)

MMP (3)

Interleukin (3)

EGFR (3)

transporter (3)

FLT (3)

STAT (3)

GPR (3)

Sodium Channel (3)

Arginase (2)

c-Met/HGFR (2)

NADPH (2)

RAAS (2)

JNK (2)

Phosphatase (2)

ABC (2)

Proteasome (2)

Mdm2 (2)

Transferase (2)

VEGFR (2)

Adrenergic Receptor (2)

IAP (2)

LDL (2)

NMDAR (2)

Tyrosine Kinases (2)

Cysteine Protease (2)

ERK (2)

Gamma-secretase (2)

Free radical scavengers (2)

cGAS (2)

PAK (2)

JAK (2)

Antiviral (2)

IκB/IKK (2)

ribosome (2)

PI4K (2)

MEK (2)

NO Synthase (2)

Casein Kinase (2)

Carboxypeptidase (2)

Retinoid Receptor (2)

Phospholipase (2)

Adenosine deaminase (2)

Cannabinoid Receptor (2)

Syk (2)

Anti-infection (2)

Microtubule Associated (2)

Thrombin (2)

HIF/HIF Prolyl-Hydroxylase (2)

Src (1)

P2Y Receptor (1)

Histamine Receptor (1)

Glutathione Peroxidase (1)

c-Myc (1)

Proton pump (1)

Hydrogenase (1)

Dopamine Receptor (1)

Histone Demethylase (1)

OCT (1)

Serine/threonin kinase (1)

Glucokinase (1)

ROCK (1)

MAO (1)

iGluR (1)

IDO (1)

Raf (1)

Leukotriene Receptor (1)

FLAP (1)

E1/E2/E3 Enzyme (1)

PAFR (1)

P2X Receptor (1)

ROS (1)

Chk (1)

Aurora Kinase (1)

P-gp (1)

HSP (1)

TLR (1)

LRRK2 (1)

PDGFR (1)

Hedgehog/Smoothened (1)

CCR (1)

PAD (1)

Epoxide Hydrolase (1)

IGF-1R (1)

Androgen Receptor (1)

MAPK (1)

Trk receptor (1)

Aminopeptidase (1)

Histone Acetyltransferase (1)

c-Fms (1)

KLF (1)

5-HT Receptor (1)

SGK (1)

MLK (1)

RSV (1)

Aromatase (1)

PLK (1)

c-RET (1)

c-Kit (1)

NOD (1)

Ras (1)

TAM Receptor (1)

FAK (1)

NOD-like Receptor (NLR) (1)

HER (1)

Monoamine Oxidase (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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