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anti_tumor_natural_product_library
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Anti-Tumor Natural Product Library
Product No.: L6700

Cancer is a well-recognized global health problem responsible for 7.6 million deaths (13% of all deaths) worldwide, which is expected to rise to 13.1 million by 2030. It has long been recognized that natural products represent the richest source of high chemical diversity, providing the basis for identification of novel scaffold structures that serves as starting points for rational anticancer drug design. According to a recent review, 49% of drugs were either natural products or their derivatives that are used in cancer treatment. Moreover, between the year 2005 and 2010, 19 natural product-based drugs have been approved, among which 7, 10 and 2 have been classified as natural product (NP), semi-synthetic NPs and NP-derived drugs, respectively. Natural products have served as an effective source of drugs and drug leads.

TargetMol carefully collects 1772 natural products from plants, animals, or microbes with known or potential antitumor activity, which is a powerful tool for your antitumor drug development and lead compounds screening.

Product No.:L6700
  • A unique collection of 1772 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
  • Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening;
  • Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information;
  • Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description;
  • Cost-effectiveness: expensive natural products with poor drug likeliness are excluded, allowing for more high-quality natural products at a lower cost.
Compound Service
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Compound library Consultation
Composition of compound library
Antibacterial (185)
NF-κB (149)
Antibiotic (88)
Reactive Oxygen Species (81)
COX (66)
Antifungal (62)
TNF (60)
Parasite (58)
Antioxidant (56)
Influenza Virus (52)
DNA/RNA Synthesis (51)
P450 (48)
ERK (47)
p38 MAPK (46)
Akt (44)
Caspase (43)
HIV Protease (42)
IL Receptor (39)
STAT (39)
AMPK (36)
Ferroptosis (31)
PI3K (31)
Topoisomerase (31)
PPAR (31)
AChR (30)
Microtubule Associated (30)
Estrogen/progestogen Receptor (29)
JNK (29)
BCL (29)
NO Synthase (29)
Dehydrogenase (26)
AChE (26)
Estrogen Receptor/ERR (25)
MMP (25)
PKC (24)
Mitophagy (23)
Virus Protease (23)
Calcium Channel (23)
Nrf2 (22)
GABA Receptor (22)
P-gp (21)
Tyrosinase (21)
Adrenergic Receptor (20)
5-HT Receptor (20)
Potassium Channel (20)
PARP (19)
HSV (19)
Wnt/beta-catenin (17)
TRP/TRPV Channel (17)
ROS (17)
Anti-infection (17)
Lipoxygenase (16)
EGFR (16)
HIF/HIF Prolyl-Hydroxylase (16)
HDAC (15)
PDE (14)
HBV (14)
Antifection (14)
JAK (14)
mTOR (14)
Sodium Channel (14)
ATPase (13)
TLR (13)
NOS (12)
VEGFR (12)
Mitochondrial Metabolism (12)
TGF-beta/Smad (12)
Androgen Receptor (12)
Antiviral (12)
Beta Amyloid (12)
Amino Acids and Derivatives (11)
Nucleoside Antimetabolite/Analog (11)
Interleukin (11)
MAPK (11)
Histamine Receptor (10)
Dopamine Receptor (10)
MAO (10)
CDK (10)
Prostaglandin Receptor (10)
Adenosine Receptor (9)
PKA (9)
Glucosidase (9)
SARS-CoV (9)
Phosphatase (8)
GluR (8)
HSP (8)
MEK (8)
Cannabinoid Receptor (8)
NOD (8)
p53 (8)
HCV Protease (7)
Glucocorticoid Receptor (7)
Immunology/Inflammation related (7)
IκB/IKK (7)
ribosome (7)
HIF (7)
Monoamine Oxidase (7)
Progesterone Receptor (6)
NMDAR (6)
Opioid Receptor (6)
Fatty Acid Synthase (6)
Sirtuin (6)
Indoleamine 2,3-Dioxygenase (IDO) (6)
HMG-CoA Reductase (6)
Carbonic Anhydrase (5)
c-Met/HGFR (5)
BACE (5)
GSK-3 (5)
iGluR (5)
IAP (5)
UGT (5)
LDL (5)
FXR (5)
Aryl Hydrocarbon Receptor (5)
Gamma-secretase (5)
Drug Metabolite (5)
Epigenetic Reader Domain (5)
CaMK (5)
transporter (5)
PTEN (5)
IGF-1R (5)
Reverse Transcriptase (5)
Aromatase (5)
Phospholipase (5)
NOD-like Receptor (NLR) (5)
HER (5)
DHFR (4)
Src (4)
Reductase (4)
NADPH (4)
Proteasome (4)
Transferase (4)
Integrin (4)
Serine/threonin kinase (4)
Tyrosine Kinases (4)
Cysteine Protease (4)
E1/E2/E3 Enzyme (4)
CXCR (4)
Xanthine Oxidase (4)
PGE Synthase (4)
Hedgehog/Smoothened (4)
GST (4)
FGFR (4)
Retinoid Receptor (4)
Platelet aggregation (4)
DNA Methyltransferase (4)
FAK (4)
Arginase (3)
RAAS (3)
Glutathione Peroxidase (3)
ABC (3)
DNA gyrase (3)
MRP (3)
cell cycle arrest (3)
Liver X Receptor (3)
P2X Receptor (3)
GPCR19 (3)
CCR (3)
Telomerase (3)
Lipid (3)
Trk receptor (3)
Aminopeptidase (3)
Histone Acetyltransferase (3)
PDK (3)
Syk (3)
S6 Kinase (3)
Imidazoline Receptor (3)
Chloride channel (2)
ROR (2)
DYRK (2)
Thyroid hormone receptor(THR) (2)
Proton pump (2)
LTR (2)
PERK (2)
Antifolate (2)
Serine Protease (2)
Glucokinase (2)
Amylase (2)
Adiponectin receptor (2)
Bcr-Abl (2)
Pim (2)
Leukotriene Receptor (2)
Smo (2)
Aurora Kinase (2)
cAMP (2)
DNA (2)
Acyltransferase (2)
Decarboxylase (2)
PDGFR (2)
PAK (2)
Norepinephrine (2)
Pyroptosis (2)
IRAK (2)
AhR (2)
PKM (2)
Casein Kinase (2)
GPR (2)
Ras (2)
Adenylyl cyclase (1)
stilbene oxidase (1)
CYP19A1 (1)
Histone Methyltransferase (1)
Dynamin (1)
LPL Receptor (1)
DNA Alkylator/Crosslinker (1)
RAR/RXR  (1)
Cell wall (1)
Melatonin Receptor (1)
c-Myc (1)
Mdm2 (1)
CAT (1)
NPC1L1 (1)
Hydrogenase (1)
MyD88 (1)
Histone Demethylase (1)
Lipase (1)
Factor Xa (1)
OCT (1)
RANKL/RANK (1)
IDO (1)
IRE1 (1)
Fas/FasL (1)
Raf (1)
Phosphorylase (1)
PAFR (1)
MTH1 (1)
Glucagon Receptor (1)
GlyT (1)
Monoamine Transporter (1)
Hexokinase (1)
Stearoyl-CoA Desaturase (SCD) (1)
Bradykinin Receptor (1)
Somatostatin (1)
ATP Citrate Lyase (1)
BCRP (1)
Beta-Secretase (1)
Free radical scavengers (1)
FAAH (1)
PAD (1)
SGLT (1)
Survivin (1)
ATM/ATR (1)
FLT (1)
CFTR (1)
hCE (1)
PAI-1 (1)
ALK (1)
RSV (1)
Carboxypeptidase (1)
CRISPR/Cas9 (1)
Hydroxylase (1)
PLK (1)
Adenosine deaminase (1)
NADPH-oxidase (1)
Thrombin (1)
ROS Kinase (1)
PD-1/PD-L1 (1)
S1P Receptor (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE