Anti-Metabolism Disease Compound Library

Product No.： L5200

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1544 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

Product No.：L5200

Product Description

A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA;
Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality;

Compound Service

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Compound library Consultation

Composition of compound library

Apoptosis (188)

P450 (155)

Endogenous Metabolite (125)

Others (107)

Dehydrogenase (85)

AMPK (81)

Antibacterial (80)

PDE (77)

PPAR (71)

PI3K (55)

Antibiotic (51)

COX (49)

Glucocorticoid Receptor (39)

MAO (37)

Reactive Oxygen Species (35)

HIV Protease (34)

HSP (34)

mTOR (32)

Parasite (31)

Ferroptosis (30)

Potassium Channel (30)

FAAH (28)

Carbonic Anhydrase (27)

NF-κB (27)

Akt (26)

Lipoxygenase (25)

Proteasome (24)

Antifungal (24)

Phosphatase (24)

Mitophagy (24)

GSK-3 (24)

Calcium Channel (24)

Phospholipase (23)

RAAS (22)

DNA/RNA Synthesis (22)

Influenza Virus (22)

Retinoid Receptor (22)

Casein Kinase (21)

Mitochondrial Metabolism (20)

HIF/HIF Prolyl-Hydroxylase (20)

Monoamine Oxidase (20)

FXR (19)

DPP-4 (18)

NADPH (17)

ROCK (17)

Glucosidase (17)

Transferase (16)

CDK (16)

5-HT Receptor (16)

Adrenergic Receptor (15)

AChR (15)

HMG-CoA Reductase (15)

SARS-CoV (14)

GPR (14)

Reductase (13)

Indoleamine 2,3-Dioxygenase (IDO) (13)

HCV Protease (12)

Adenosine Receptor (12)

Virus Protease (12)

PKA (12)

IL Receptor (12)

Prostaglandin Receptor (12)

ATM/ATR (12)

Sodium Channel (12)

AhR (12)

DHFR (11)

DNA-PK (11)

Lipase (11)

Histamine Receptor (11)

HBV (11)

PARP (11)

Glucokinase (11)

ERK (11)

Fatty Acid Synthase (11)

MMP (11)

SGLT (11)

GABA Receptor (11)

HIF (11)

TNF (11)

S6 Kinase (11)

ROR (10)

Wnt/beta-catenin (10)

PKC (10)

transporter (10)

Tyrosinase (10)

Estrogen/progestogen Receptor (9)

Estrogen Receptor/ERR (9)

Serine Protease (9)

Liver X Receptor (9)

Caspase (9)

ROS (9)

Hydroxylase (9)

Cannabinoid Receptor (9)

ATPase (8)

JNK (8)

Glutathione Peroxidase (8)

Factor Xa (8)

Antifolate (8)

NAMPT (8)

Aryl Hydrocarbon Receptor (8)

Isocitrate Dehydrogenase (IDH) (8)

HSV (8)

Xanthine Oxidase (8)

Interleukin (8)

AChE (8)

IκB/IKK (8)

Reverse Transcriptase (8)

STAT (8)

PDK (8)

Thrombin (8)

NO Synthase (8)

Dopamine Receptor (7)

Cysteine Protease (7)

IDO (7)

Topoisomerase (7)

UGT (7)

Glucagon Receptor (7)

Stearoyl-CoA Desaturase (SCD) (7)

Lipid (7)

Nrf2 (7)

PAI-1 (7)

HDAC (7)

PKM (7)

Src (6)

VEGFR (6)

TRP/TRPV Channel (6)

Phosphorylase (6)

Opioid Receptor (6)

P-gp (6)

Acyltransferase (6)

Aminopeptidase (6)

Sirtuin (6)

Neprilysin (6)

Chloride channel (5)

p38 MAPK (5)

c-Met/HGFR (5)

CETP (5)

iGluR (5)

BCL (5)

Androgen Receptor (5)

Beta Amyloid (5)

MEK (5)

SGK (5)

FLT (5)

Microtubule Associated (5)

NOS (4)

CAT (4)

Serine/threonin kinase (4)

LDL (4)

JAK (4)

CCR (4)

Aurora Kinase (4)

GluR (4)

Norepinephrine (4)

DNA (4)

TGF-beta/Smad (4)

ATP Citrate Lyase (4)

GPCR19 (4)

RSV (4)

ribosome (4)

Anti-infection (4)

Thyroid hormone receptor(THR) (3)

NPC1L1 (3)

Integrin (3)

P2Y Receptor (3)

BACE (3)

PERK (3)

ABC (3)

MRP (3)

Leukotriene Receptor (3)

SIK (3)

Annexin A (3)

Adiponectin receptor (3)

Drug Metabolite (3)

Antifection (3)

Hexokinase (3)

Vasopressin Receptor (3)

Endothelin Receptor (3)

IGF-1R (3)

CaMK (3)

OAT (3)

Decarboxylase (3)

Acetyl-CoA Carboxylase (3)

Carboxypeptidase (3)

c-RET (3)

FGFR (3)

NADPH-oxidase (3)

Ras (3)

TAM Receptor (3)

Proton pump (2)

Histone Methyltransferase (2)

Amino Acids and Derivatives (2)

Antioxidant (2)

Histone Demethylase (2)

Progesterone Receptor (2)

Tyrosine Kinases (2)

Rho (2)

cell cycle arrest (2)

Nucleoside Antimetabolite/Analog (2)

Glutaminase (2)

E1/E2/E3 Enzyme (2)

PDGFR (2)

PAK (2)

Hedgehog/Smoothened (2)

PGC-1α (2)

Chk (2)

OX Receptor (2)

Epoxide Hydrolase (2)

Epigenetic Reader Domain (2)

EGFR (2)

MAPK (2)

Antiviral (2)

Trk receptor (2)

ASK (2)

ALK (2)

GST (2)

Adenosine deaminase (2)

Neurokinin receptor (2)

Gap Junction Protein (2)

Syk (2)

c-Kit (2)

Sigma receptor (2)

ROS Kinase (2)

CFTR (2)

p53 (2)

MLK (2)

advanced glycation end products (1)

Mdm2 (1)

Adenylyl cyclase (1)

GSNOR (1)

Transaminase (1)

Monocarboxylate transporter (1)

stilbene oxidase (1)

Hydrogenase (1)

DprE1 (1)

Arginase (1)

YAP (1)

LPL Receptor (1)

DNA Alkylator/Crosslinker (1)

LTR (1)

IFNAR (1)

aconitase (1)

DYRK (1)

RAR/RXR (1)

Tie-2 (1)

Melatonin Receptor (1)

Galectin (1)

CaSR (1)

N-Acetylglucosaminyltransferase (1)

Pim (1)

Serotonin Transporter (1)

Immunology/Inflammation related (1)

CSF-1R (1)

IAP (1)

FLAP (1)

RIP kinase (1)

Bcr-Abl (1)

FABP (1)

GRK (1)

MT Receptor (1)

NMDAR (1)

DNA gyrase (1)

Monoamine Transporter (1)

Anion Exchanger (1)

Guanylate cyclase (1)

Smo (1)

PROTAC Linker (1)

MAGL (1)

Bombesin Receptor (1)

DNA Alkylation (1)

Thioredoxin (1)

Bradykinin Receptor (1)

CXCR (1)

PAD (1)

Telomerase (1)

BCRP (1)

Beta-Secretase (1)

PGE Synthase (1)

Glutathione reductase (1)

TLR (1)

LRRK2 (1)

Free radical scavengers (1)

GluCls (1)

hCE (1)

Pyroptosis (1)

MELK (1)

c-Fms (1)

LPA Receptor (1)

Aromatase (1)

PI4K (1)

CRISPR/Cas9 (1)

Complement System (1)

Platelet aggregation (1)

BMI-1 (1)

DNA Methyltransferase (1)

cholecystokinin (1)

S1P Receptor (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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