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anti_inflammatory_traditional_chinese_medicine_compound_library
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Anti-Inflammatory Traditional Chinese Medicine Compound Library
Product No.: L6710

Inflammation is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. The classical characteristics of inflammation are pain, swelling, edema, redness and heat. Anti-inflammatory drugs are the second most commonly clinically used drugs. The widely used anti-inflammatory drugs include non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. However, both have a wide range of side effects. As research advanced, various natural products from traditional Chinese medicine (TCM) have been demonstrated in many animal or cell culture models to safely suppress proinflammatory pathways and control inflammation-associated disease. Plant chemical constituents are one of the richest hot spots for most significant new drug discoveries. Herbal medicines have gained special interest in recent years as a subject of both commercial and scientific interests.

TargetMol collects 1246 TCM monomers with anti-inflammatory activity in this library, including Flavone, Saponins, Terpenes, Alkaloids, etc. derived from herbs such as honeysuckle, Coptis chinensis, Baical Skullcap Root, Panax notoginseng, etc. With its diversity of compound structures and detailed information about bioactivity, it is a powerful tool for research in anti-inflammation.

Product No.:L6710
  • A collection of 1246 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
  • Covers various targets such as COX, CCR, STAT, TGFβ, etc. involved in inflammation;
  • Diversity: includes Flavone, Saponins, Terpenes, Alkaloids, etc.;
  • NMR and HPLC validated to ensure high purity and quality.
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Composition of compound library
Endogenous Metabolite (189)
NF-κB (167)
Autophagy (157)
Antibacterial (131)
COX (85)
Reactive Oxygen Species (81)
Antioxidant (58)
TNF (57)
Influenza Virus (47)
Antifungal (45)
NO Synthase (43)
IL Receptor (42)
Parasite (41)
p38 MAPK (40)
P450 (35)
STAT (34)
ERK (33)
HIV Protease (29)
Akt (28)
Virus Protease (25)
ROS (24)
AChE (24)
JNK (23)
Nrf2 (23)
NOS (22)
MMP (21)
Antibiotic (21)
PPAR (20)
Caspase (19)
Calcium Channel (19)
Immunology/Inflammation related (19)
AMPK (19)
AChR (19)
Ferroptosis (17)
Lipoxygenase (17)
Prostaglandin Receptor (17)
Mitophagy (16)
DNA/RNA Synthesis (16)
GABA Receptor (16)
Anti-infection (16)
TRP/TRPV Channel (15)
EGFR (15)
Antiviral (15)
PI3K (14)
BCL (14)
Beta Amyloid (14)
Potassium Channel (14)
Tyrosinase (14)
PDE (13)
HSV (13)
Interleukin (13)
JAK (13)
Estrogen Receptor/ERR (12)
Topoisomerase (12)
5-HT Receptor (12)
Estrogen/progestogen Receptor (11)
Wnt/beta-catenin (11)
PKC (11)
TLR (11)
ATPase (10)
Adenosine Receptor (10)
Antifection (10)
HBV (9)
TGF-beta/Smad (9)
HDAC (9)
P-gp (8)
mTOR (8)
Sodium Channel (8)
HCV Protease (7)
Dehydrogenase (7)
Adrenergic Receptor (7)
Mitochondrial Metabolism (7)
Opioid Receptor (7)
IκB/IKK (7)
Histamine Receptor (6)
VEGFR (6)
MAO (6)
CDK (6)
Drug Metabolite (6)
SARS-CoV (6)
transporter (6)
MAPK (6)
Phospholipase (6)
HIF/HIF Prolyl-Hydroxylase (6)
HER (6)
Reductase (5)
Proteasome (5)
PARP (5)
Gamma-secretase (5)
Glucosidase (5)
Cannabinoid Receptor (5)
Microtubule Associated (5)
p53 (5)
Arginase (4)
Phosphatase (4)
PKA (4)
Fatty Acid Synthase (4)
CXCR (4)
CaMK (4)
PGE Synthase (4)
HSP (4)
IGF-1R (4)
Indoleamine 2,3-Dioxygenase (IDO) (4)
NOD (4)
Carbonic Anhydrase (3)
c-Met/HGFR (3)
BACE (3)
RAAS (3)
IAP (3)
UGT (3)
MRP (3)
Nucleoside Antimetabolite/Analog (3)
Aryl Hydrocarbon Receptor (3)
Xanthine Oxidase (3)
Epigenetic Reader Domain (3)
Free radical scavengers (3)
Sirtuin (3)
FAAH (3)
PTEN (3)
MEK (3)
FGFR (3)
Reverse Transcriptase (3)
Aromatase (3)
HIF (3)
Platelet aggregation (3)
Syk (3)
S6 Kinase (3)
FAK (3)
NOD-like Receptor (NLR) (3)
Monoamine Oxidase (3)
Chloride channel (2)
ROR (2)
Src (2)
DYRK (2)
NADPH (2)
Glutathione Peroxidase (2)
GSK-3 (2)
Proton pump (2)
Integrin (2)
Amino Acids and Derivatives (2)
LTR (2)
Lipase (2)
Serine/threonin kinase (2)
Glucokinase (2)
RANKL/RANK (2)
Amylase (2)
Glucocorticoid Receptor (2)
iGluR (2)
LDL (2)
Tyrosine Kinases (2)
Pim (2)
cell cycle arrest (2)
Cysteine Protease (2)
Liver X Receptor (2)
Leukotriene Receptor (2)
PAFR (2)
Monoamine Transporter (2)
Aurora Kinase (2)
Acyltransferase (2)
Hedgehog/Smoothened (2)
CCR (2)
Telomerase (2)
Lipid (2)
OAT (2)
Pyroptosis (2)
IRAK (2)
AhR (2)
PAI-1 (2)
Casein Kinase (2)
NADPH-oxidase (2)
Thrombin (2)
Adenylyl cyclase (1)
stilbene oxidase (1)
CD38 (1)
DHFR (1)
Dynamin (1)
Progesterone Receptor (1)
Melatonin Receptor (1)
c-Myc (1)
advanced glycation end products (1)
Mdm2 (1)
Transferase (1)
Dopamine Receptor (1)
MyD88 (1)
IFNAR (1)
Histone Demethylase (1)
Factor Xa (1)
CaSR (1)
Adiponectin receptor (1)
Bcr-Abl (1)
Raf (1)
Phosphorylase (1)
DNA gyrase (1)
Serotonin Transporter (1)
FXR (1)
E1/E2/E3 Enzyme (1)
P2X Receptor (1)
Smo (1)
DPP-4 (1)
cAMP (1)
GluR (1)
Thrombopoietin Receptor (1)
Decarboxylase (1)
Bombesin Receptor (1)
PDGFR (1)
PAD (1)
Epoxide Hydrolase (1)
Norepinephrine (1)
Androgen Receptor (1)
SGLT (1)
Survivin (1)
Trk receptor (1)
Aminopeptidase (1)
Histone Acetyltransferase (1)
ATM/ATR (1)
GST (1)
ribosome (1)
PDK (1)
HMG-CoA Reductase (1)
CFTR (1)
PKM (1)
hCE (1)
ALK (1)
RSV (1)
Retinoid Receptor (1)
CRISPR/Cas9 (1)
GPR (1)
Oxytocin Receptor (1)
PLK (1)
DNA Methyltransferase (1)
Ras (1)
ROS Kinase (1)
Imidazoline Receptor (1)
PD-1/PD-L1 (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE