Gastroenteritis is inflammation of the lining of the stomach and small and large intestines. Most cases are infectious, although gastroenteritis may occur after ingestion of drugs and chemical toxins (eg, metals, plant substances). In the US, an estimated 1 in 6 people contracts foodborne illness each year. Worldwide, an estimated 1.5 million children die each year from infectious gastroenteritis.
Compounds derived from natural products have demonstrated their effectiveness as therapeutic agents in different areas, such as cancer, aging, metabolic disorder, cardiovascular disease (controlling blood sugar), inflammation (gastroprotective effect), and neurologic disorders, etc. Gastrointestinal tract is where the natural products exert their bioactivities, such as modulating the movement of gastrointestinal tract, protecting stomach mucosa, keeping gut bacteria in balance, and interacting with intestinal immune system. Understanding the effects of natural products on gastrointestinal function is of significance to the treatment of related gastrointestinal diseases and drug screening.
Anti-Gastroenteritis Natural Product Library by TargetMol is a unique collection of 219 natural products related to gastroenteritis, an effective tool for research in gastric function and related diseases, drug screening.
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Vadadustat | TAK875 | TAK-779 | Tegobuvir | RN-1734 | BMS-687453 | AM211 | FT011 | BMS754807 | AAI101 | ||
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RPW-24 | SRT1720 hydrochloride | INH6 | SRT 2183 | AMG208 | Pentadecanoic acid | Apiopaeonoside | Pemirolast potassium | L-Anserine nitrate salt | Sodium Picosulfate | ||
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Lercanidipine | Cobicistat | 1-Ethyl-2-benzimidazolinone | ROSIRIDIN | PF-AKT400 | Benzyl alcohol | 1-Methylnicotinamide chloride | MX69 | CVT-10216 | LCL161 | ||
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Tirasemtiv | Roniacol | Rg3039 | Z433927330 | Desloratadine | CH5132799 | 5-Bromoindole | Smurf1-IN-A01 | Halosulfuron-methyl | Piceatannol | ||
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ML346 | SB 4 | Daclatasvir | Daclatasvir dihydrochloride | NADPH (tetracyclohexanamine) | AZD8055 | Vistusertib | PAβN dihydrochloride | HZ1157 | Rotundine | ||
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Thiamet G | B-AP15 | Silmitasertib | Levofloxacin | Pamicogrel | GSK369796 Dihydrochloride | 2-Chloronaphthoquinone | TFAP | Tenovin3 | Azvudine | ||
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Milnacipran hydrochloride | BW-A78U | Tenovin-6 | DL-Normetanephrine hydrochloride | Triclocarban | CUDC101 | Chlorpropham | Mestinon | Zacopride hydrochloride | PF04691502 | ||
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L-Hyoscyamine | Noreugenin | ML-030 | BC-1382 | Gadolinium chloride | Vorolanib | VTP-27999 TFA | GSK0660 | Lomerizine hydrochloride | 8-CHLOROQUINAZOLIN-4(1H)-ONE |