Anti-Fibrosis Compound Library

Product No.： L9810

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol’s Anti-Fibrosis Compound Library collects 1180 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

Product No.：L9810

Product features

A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
Targets include TGFβ、TNFα、MMP、EGFR、NADPH-oxidase, etc.
Some compounds are in the market (FDA-approved)；
Detailed compound information with structure, target, IC50, and biological activity description；
NMR and HPLC/LCMS validated to ensure high purity and quality.

Compound Service

Our compound library can be flexibly customized！View More

Compound library Consultation

Composition of compound library

Apoptosis (199)

Others (169)

Autophagy (154)

Reactive Oxygen Species (129)

Endogenous Metabolite (114)

COX (112)

VEGFR (91)

Antibacterial (89)

MMP (78)

Antioxidant (77)

NF-κB (74)

TNF (69)

TGF-beta/Smad (63)

FGFR (57)

PDGFR (56)

Wnt/beta-catenin (41)

ROS (39)

IL Receptor (34)

c-Kit (34)

FLT (32)

Antifungal (30)

Parasite (30)

Influenza Virus (27)

ALK (26)

EGFR (25)

Glucocorticoid Receptor (22)

JAK (22)

STAT (22)

Antibiotic (22)

Ferroptosis (21)

NADPH (21)

p38 MAPK (20)

ERK (20)

HIV Protease (19)

Src (19)

P450 (19)

NO Synthase (19)

Cannabinoid Receptor (18)

c-Met/HGFR (17)

PPAR (17)

CFTR (16)

Mitophagy (15)

Virus Protease (15)

Nrf2 (15)

Caspase (13)

DNA/RNA Synthesis (13)

NOS (12)

Bcr-Abl (12)

Interleukin (12)

AMPK (12)

c-RET (12)

PARP (11)

Calcium Channel (11)

PDE (11)

Lipoxygenase (11)

Akt (11)

PI3K (10)

PKC (10)

BCL (10)

Prostaglandin Receptor (10)

Anti-infection (10)

Tyrosinase (10)

JNK (9)

Tyrosine Kinases (9)

CDK (9)

Mitochondrial Metabolism (9)

Aurora Kinase (9)

Estrogen/progestogen Receptor (8)

Raf (8)

TLR (8)

Trk receptor (8)

GABA Receptor (8)

HIF/HIF Prolyl-Hydroxylase (8)

ROS Kinase (8)

Dehydrogenase (7)

Topoisomerase (7)

SARS-CoV (7)

IκB/IKK (7)

Potassium Channel (7)

TRP/TRPV Channel (6)

Adrenergic Receptor (6)

HSV (6)

Xanthine Oxidase (6)

AChE (6)

P-gp (6)

Beta Amyloid (6)

c-Fms (6)

LPA Receptor (6)

Phospholipase (6)

NADPH-oxidase (6)

NOD-like Receptor (NLR) (6)

HER (6)

ATPase (5)

LPL Receptor (5)

Adenosine Receptor (5)

Glutathione Peroxidase (5)

PKA (5)

Estrogen Receptor/ERR (5)

CSF-1R (5)

Immunology/Inflammation related (5)

CCR (5)

Antiviral (5)

5-HT Receptor (5)

Syk (5)

Sodium Channel (5)

S6 Kinase (5)

TAM Receptor (5)

Chloride channel (4)

Reductase (4)

Histamine Receptor (4)

GSK-3 (4)

Cysteine Protease (4)

Drug Metabolite (4)

Chk (4)

Epigenetic Reader Domain (4)

PGE Synthase (4)

MAPK (4)

Free radical scavengers (4)

HDAC (4)

HIF (4)

MEK (4)

AChR (4)

NOD (4)

HCV Protease (3)

RAAS (3)

Phosphatase (3)

Serine Protease (3)

Serine/threonin kinase (3)

Annexin A (3)

UGT (3)

Glucosidase (3)

Molecular Glues (3)

FAAH (3)

mTOR (3)

HSP (3)

Sirtuin (3)

Ephrin Receptor (3)

Casein Kinase (3)

Reverse Transcriptase (3)

Retinoid Receptor (3)

Ligand for E3 Ligase (3)

ribosome (3)

GPR (3)

PDK (3)

Monoamine Oxidase (3)

Proteasome (2)

ROR (2)

Histone Methyltransferase (2)

Integrin (2)

LTR (2)

BACE (2)

Lipase (2)

Tie-2 (2)

MRP (2)

HBV (2)

Leukotriene Receptor (2)

MAO (2)

IAP (2)

IRE1 (2)

RIP kinase (2)

Gamma-secretase (2)

P2X Receptor (2)

DNA gyrase (2)

Antifection (2)

Opioid Receptor (2)

Smo (2)

Hedgehog/Smoothened (2)

CXCR (2)

PTEN (2)

Epoxide Hydrolase (2)

IGF-1R (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Porcupine (2)

Aminopeptidase (2)

Histone Acetyltransferase (2)

PAI-1 (2)

RSV (2)

Aromatase (2)

Gap Junction Protein (2)

Discoidin Domain Receptor (DDR) (2)

Microtubule Associated (2)

FAK (2)

MLK (2)

p53 (2)

advanced glycation end products (1)

Proton pump (1)

Carbonic Anhydrase (1)

Transferase (1)

Monocarboxylate transporter (1)

Hydrogenase (1)

Dynamin (1)

MyD88 (1)

Amino Acids and Derivatives (1)

IFNAR (1)

RAR/RXR (1)

Progesterone Receptor (1)

Melatonin Receptor (1)

Galectin (1)

c-Myc (1)

CaSR (1)

N-Acetylglucosaminyltransferase (1)

Rho (1)

Hck (1)

cell cycle arrest (1)

Liver X Receptor (1)

RANKL/RANK (1)

ROCK (1)

Amylase (1)

iGluR (1)

FLAP (1)

E1/E2/E3 Enzyme (1)

Adiponectin receptor (1)

LDL (1)

AAK1 (AP2 associated kinase 1) (1)

Phosphorylase (1)

BTK (1)

Anion Exchanger (1)

Guanylate cyclase (1)

PAK (1)

Somatostatin (1)

PAD (1)

CaMK (1)

DNA (1)

Androgen Receptor (1)

Telomerase (1)

SGLT (1)

ATP Citrate Lyase (1)

OXPHOS (1)

Glutathione reductase (1)

Survivin (1)

transporter (1)

ASK (1)

hCE (1)

Pyroptosis (1)

ATM/ATR (1)

GST (1)

Hydroxylase (1)

PLK (1)

Platelet aggregation (1)

DNA Methyltransferase (1)

IRAK (1)

Ras (1)

HMG-CoA Reductase (1)

Thrombin (1)

PKM (1)

Example of compound library information

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

Specification	Special Discount Waiting for you to inquire！
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