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anti_cardiovascular_disease_compound_library
/library/anti_cardiovascular_disease_compound_library
Anti-Cardiovascular Disease Compound Library
Product No.: L5400

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1408 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

Product No.:L5400
  • A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
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Composition of compound library
Autophagy (161)
VEGFR (154)
Calcium Channel (147)
Apoptosis (147)
Adrenergic Receptor (140)
Others (136)
COX (95)
Endogenous Metabolite (88)
Sodium Channel (82)
PDE (75)
PDGFR (57)
TNF (56)
5-HT Receptor (48)
TGF-beta/Smad (47)
RAAS (45)
Antibacterial (45)
AChR (43)
Potassium Channel (42)
Dopamine Receptor (40)
c-Kit (39)
FGFR (37)
FLT (37)
NF-κB (36)
IL Receptor (35)
PARP (29)
Reactive Oxygen Species (28)
CDK (26)
Histamine Receptor (25)
MMP (25)
Parasite (22)
PPAR (21)
PKC (21)
JAK (20)
ALK (19)
c-Met/HGFR (18)
IGF-1R (18)
EGFR (17)
Antibiotic (17)
ATPase (16)
Carbonic Anhydrase (16)
Src (16)
p38 MAPK (16)
Ferroptosis (16)
c-RET (16)
HIV Protease (15)
Adenosine Receptor (15)
Mitophagy (15)
Prostaglandin Receptor (15)
P450 (15)
Thrombin (15)
Antifungal (14)
Norepinephrine (14)
HMG-CoA Reductase (14)
Endothelin Receptor (13)
NO Synthase (13)
ERK (12)
DNA/RNA Synthesis (12)
Influenza Virus (12)
Raf (11)
Akt (11)
BACE (10)
Tyrosine Kinases (10)
Rho (10)
Glucocorticoid Receptor (10)
P-gp (10)
Histone Acetyltransferase (10)
Antioxidant (9)
Serotonin Transporter (9)
Drug Metabolite (9)
Beta Amyloid (9)
AMPK (9)
GABA Receptor (9)
Proton pump (8)
P2Y Receptor (8)
iGluR (8)
Bcr-Abl (8)
Guanylate cyclase (8)
Aurora Kinase (8)
Interleukin (8)
Beta-Secretase (8)
STAT (8)
MEK (8)
PI3K (7)
GSK-3 (7)
Virus Protease (7)
MRP (7)
PKA (7)
TRP/TRPV Channel (7)
ROCK (7)
Topoisomerase (7)
NMDAR (7)
ROS (7)
CaMK (7)
Phospholipase (7)
Ras (7)
TAM Receptor (7)
HIF/HIF Prolyl-Hydroxylase (7)
Dehydrogenase (6)
Factor Xa (6)
Caspase (6)
Trk receptor (6)
Nrf2 (6)
IκB/IKK (6)
Acetyl-CoA Carboxylase (6)
c-Fms (6)
HDAC (6)
Tyrosinase (6)
NADPH (5)
JNK (5)
Wnt/beta-catenin (5)
Nucleoside Antimetabolite/Analog (5)
Opioid Receptor (5)
HSV (5)
Lipoxygenase (5)
Hydroxylase (5)
HIF (5)
Syk (5)
Proteasome (4)
Chloride channel (4)
NOS (4)
Estrogen/progestogen Receptor (4)
CETP (4)
Tie-2 (4)
Serine Protease (4)
MAO (4)
Mitochondrial Metabolism (4)
BCL (4)
Chk (4)
GluR (4)
Epigenetic Reader Domain (4)
mTOR (4)
SARS-CoV (4)
Ephrin Receptor (4)
RSV (4)
Neprilysin (4)
GPR (4)
Anti-infection (4)
NOD (4)
Microtubule Associated (4)
FAK (4)
NOD-like Receptor (NLR) (4)
p53 (4)
Monoamine Oxidase (4)
Thyroid hormone receptor(THR) (3)
Arginase (3)
DNA Alkylator/Crosslinker (3)
Glutathione Peroxidase (3)
ABC (3)
Antifolate (3)
Serine/threonin kinase (3)
Liver X Receptor (3)
FXR (3)
Leukotriene Receptor (3)
CSF-1R (3)
P2X Receptor (3)
Molecular Glues (3)
DPP-4 (3)
Fatty Acid Synthase (3)
DNA Alkylation (3)
Bradykinin Receptor (3)
SGLT (3)
PGE Synthase (3)
AChE (3)
Acyltransferase (3)
TLR (3)
Casein Kinase (3)
GST (3)
Reverse Transcriptase (3)
Ligand for E3 Ligase (3)
PDK (3)
S6 Kinase (3)
MLK (3)
Imidazoline Receptor (3)
HER (3)
DHFR (2)
HCV Protease (2)
Integrin (2)
Amino Acids and Derivatives (2)
LTR (2)
Na+/Ca2+ Exchanger (2)
Histone Demethylase (2)
CaSR (2)
Estrogen Receptor/ERR (2)
HBV (2)
PYK2 (2)
Myosin (2)
IRE1 (2)
FLAP (2)
RIP kinase (2)
PAFR (2)
LDL (2)
Na-K-Cl cotransporter (2)
Antifection (2)
Monoamine Transporter (2)
CCR (2)
Xanthine Oxidase (2)
Epoxide Hydrolase (2)
cAMP (2)
Androgen Receptor (2)
Lipid (2)
MAPK (2)
LRRK2 (2)
Sirtuin (2)
transporter (2)
SGK (2)
Gap Junction Protein (2)
Platelet aggregation (2)
NADPH-oxidase (2)
DNA Methyltransferase (2)
Protease-activated Receptor (2)
AhR (2)
CFTR (2)
Adenylyl cyclase (1)
Transferase (1)
NPC1L1 (1)
ROR (1)
DNA-PK (1)
Histone Methyltransferase (1)
DprE1 (1)
Ligands for Target Protein for PROTAC (1)
Reductase (1)
IFNAR (1)
Arrestin (1)
Lipase (1)
TOPK (1)
Phosphatase (1)
Progesterone Receptor (1)
N-Acetylglucosaminyltransferase (1)
VDAC (1)
cell cycle arrest (1)
Cysteine Protease (1)
Glucokinase (1)
Amylase (1)
Aryl Hydrocarbon Receptor (1)
IAP (1)
Immunology/Inflammation related (1)
Adiponectin receptor (1)
UGT (1)
Gamma-secretase (1)
DNA gyrase (1)
GlyT (1)
BTK (1)
Anion Exchanger (1)
Isocitrate Dehydrogenase (IDH) (1)
HCN Channel (1)
Hedgehog/Smoothened (1)
FAAH (1)
Vasopressin Receptor (1)
CXCR (1)
PAD (1)
ACK (1)
Thrombopoietin Receptor (1)
DNA (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
ATP Citrate Lyase (1)
BCRP (1)
Antiviral (1)
HSP (1)
Free radical scavengers (1)
Aminopeptidase (1)
GPCR19 (1)
Decarboxylase (1)
ASK (1)
PAI-1 (1)
Pyroptosis (1)
Retinoid Receptor (1)
Melanocortin Receptor (1)
CRISPR/Cas9 (1)
PLK (1)
Discoidin Domain Receptor (DDR) (1)
Neurokinin receptor (1)
IRAK (1)
Sigma receptor (1)
PKM (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE