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anti_cancer_clinical_compound_library
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Anti-Cancer Clinical Compound Library
Product No.: L2120

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 2545 anti-cancer compounds currently in clinical trial phases based on published literatures and database to form this collection that can be used for high throughput screening and high content screening.

Product No.:L2120
  • A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity confirmed by pre-clinical research and all of them are currently in clinical trial phases, representing the cutting-edge treatments for cancers;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
Compound Service
Our compound library can be flexibly customized!View More
Compound library Consultation
Composition of compound library
Others (197)
5-HT Receptor (153)
Endogenous Metabolite (117)
Adrenergic Receptor (115)
DNA/RNA Synthesis (99)
Antibacterial (90)
Dopamine Receptor (88)
Antibiotic (88)
COX (84)
Histamine Receptor (80)
VEGFR (77)
Sodium Channel (69)
Calcium Channel (67)
EGFR (65)
PI3K (63)
Potassium Channel (60)
FLT (55)
CDK (52)
PDGFR (50)
P450 (50)
Glucocorticoid Receptor (48)
JAK (46)
c-Kit (46)
HIV Protease (45)
Parasite (45)
Reactive Oxygen Species (45)
Topoisomerase (44)
FGFR (44)
PPAR (41)
mTOR (41)
HDAC (41)
Microtubule Associated (39)
c-Met/HGFR (38)
Dehydrogenase (35)
Ferroptosis (35)
Prostaglandin Receptor (35)
NF-κB (35)
AChR (35)
Src (34)
Mitophagy (34)
Antifungal (33)
GABA Receptor (33)
Nucleoside Antimetabolite/Analog (30)
Tyrosine Kinases (29)
SARS-CoV (28)
GPR (28)
Estrogen/progestogen Receptor (27)
Adenosine Receptor (27)
Influenza Virus (27)
Bcr-Abl (26)
Raf (26)
Androgen Receptor (26)
HER (24)
iGluR (23)
PDE (23)
Opioid Receptor (23)
Akt (23)
Estrogen Receptor/ERR (22)
PARP (22)
Aurora Kinase (22)
Epigenetic Reader Domain (21)
MEK (21)
BTK (20)
p38 MAPK (19)
P-gp (19)
HSP (19)
Serotonin Transporter (18)
HSV (18)
Norepinephrine (18)
RAAS (17)
ERK (17)
Trk receptor (17)
ALK (17)
c-RET (17)
ATPase (16)
DNA Alkylator/Crosslinker (16)
HBV (16)
TRP/TRPV Channel (16)
ROS (16)
HCV Protease (15)
GSK-3 (15)
NMDAR (15)
CXCR (15)
HIF/HIF Prolyl-Hydroxylase (15)
Proton pump (14)
Phosphatase (14)
Virus Protease (14)
PKC (14)
Endothelin Receptor (14)
SGLT (14)
c-Fms (14)
TAM Receptor (14)
DNA-PK (13)
E1/E2/E3 Enzyme (13)
Guanylate cyclase (13)
BCL (13)
Chk (13)
Retinoid Receptor (13)
STAT (13)
TNF (13)
Proteasome (12)
Carbonic Anhydrase (12)
LPL Receptor (12)
Progesterone Receptor (12)
Caspase (12)
Reverse Transcriptase (12)
AMPK (12)
HIF (12)
S1P Receptor (12)
Histone Methyltransferase (11)
GNRH Receptor (11)
Antifolate (11)
Gamma-secretase (11)
DNA Alkylation (11)
IL Receptor (11)
MMP (11)
CFTR (11)
p53 (11)
Antioxidant (10)
P2X Receptor (10)
Mitochondrial Metabolism (10)
Hedgehog/Smoothened (10)
IGF-1R (10)
TGF-beta/Smad (10)
Nrf2 (10)
Syk (10)
Transferase (9)
DHFR (9)
P2Y Receptor (9)
Wnt/beta-catenin (9)
CSF-1R (9)
Antifection (9)
Vasopressin Receptor (9)
Interleukin (9)
Cannabinoid Receptor (9)
HMG-CoA Reductase (9)
S6 Kinase (9)
FAK (9)
JNK (8)
MRP (8)
PKA (8)
ROCK (8)
IAP (8)
OX Receptor (8)
GluR (8)
Lipoxygenase (8)
Indoleamine 2,3-Dioxygenase (IDO) (8)
TLR (8)
Casein Kinase (8)
ATM/ATR (8)
Beta Amyloid (8)
PLK (8)
Neurokinin receptor (8)
Ras (8)
ROS Kinase (8)
Mdm2 (7)
Integrin (7)
Pim (7)
MAO (7)
Drug Metabolite (7)
Smo (7)
Sirtuin (7)
Ligand for E3 Ligase (7)
DNA Methyltransferase (7)
Sigma receptor (7)
Kinesin (7)
Monoamine Oxidase (7)
RIP kinase (6)
Glucagon Receptor (6)
Isocitrate Dehydrogenase (IDH) (6)
PAK (6)
Bradykinin Receptor (6)
DNA (6)
IκB/IKK (6)
Phospholipase (6)
IRAK (6)
NADPH (5)
Histone Demethylase (5)
Tie-2 (5)
Glutathione Peroxidase (5)
Serine Protease (5)
Leukotriene Receptor (5)
DPP-4 (5)
CCR (5)
AChE (5)
Ephrin Receptor (5)
GHSR (5)
Hydroxylase (5)
Thrombin (5)
NO Synthase (5)
Chloride channel (4)
IFNAR (4)
Melatonin Receptor (4)
CaSR (4)
Aryl Hydrocarbon Receptor (4)
IDO (4)
Monoamine Transporter (4)
Molecular Glues (4)
Fatty Acid Synthase (4)
Xanthine Oxidase (4)
KSP (4)
CaMK (4)
Wee1 (4)
PGE Synthase (4)
Antiviral (4)
Aminopeptidase (4)
GPCR19 (4)
CRFR (4)
ribosome (4)
Aromatase (4)
CGRP Receptor (4)
cholecystokinin (4)
AhR (4)
ROR (3)
CRM1 (3)
YAP (3)
LTR (3)
ABC (3)
Rho (3)
Serine/threonin kinase (3)
FXR (3)
NAMPT (3)
Annexin A (3)
MT Receptor (3)
Na-K-Cl cotransporter (3)
Neuropeptide Y Receptor (3)
Somatostatin (3)
DUB (3)
OAT (3)
STING (3)
Free radical scavengers (3)
RSV (3)
Melanocortin Receptor (3)
PDK (3)
Oxytocin Receptor (3)
Adenosine deaminase (3)
Protease-activated Receptor (3)
PD-1/PD-L1 (3)
PROTACs (2)
NOS (2)
NEDD8 (2)
Amino Acids and Derivatives (2)
Ligands for Target Protein for PROTAC (2)
Arginase (2)
Reductase (2)
Cell wall (2)
PERK (2)
VDA (2)
Cysteine Protease (2)
Liver X Receptor (2)
PYK2 (2)
IRE1 (2)
LDL (2)
Glucosidase (2)
Hexokinase (2)
Telomerase (2)
ATP Citrate Lyase (2)
BCRP (2)
Beta-Secretase (2)
MAPK (2)
Acyltransferase (2)
Porcupine (2)
CD73 (2)
transporter (2)
Decarboxylase (2)
GST (2)
LPA Receptor (2)
Gap Junction Protein (2)
Discoidin Domain Receptor (DDR) (2)
p97 (2)
NOD-like Receptor (NLR) (2)
MLK (2)
advanced glycation end products (1)
CAT (1)
NPC1L1 (1)
Monocarboxylate transporter (1)
Hydrogenase (1)
MALT (1)
RAR/RXR  (1)
DYRK (1)
TOPK (1)
GTPase (1)
Factor Xa (1)
Galectin (1)
c-Myc (1)
Kisspeptin (1)
N-Acetylglucosaminyltransferase (1)
Hck (1)
Glucokinase (1)
Stemness kinase (1)
Glutaminase (1)
Myosin (1)
Motilin Receptor (1)
UGT (1)
PAFR (1)
MTH1 (1)
GRK (1)
DNA gyrase (1)
GlyT (1)
Anion Exchanger (1)
PROTAC Linker (1)
HCN Channel (1)
Thioredoxin (1)
ACK (1)
Lipid (1)
Survivin (1)
MNK (1)
Histone Acetyltransferase (1)
ASK (1)
GluCls (1)
PAI-1 (1)
Pyroptosis (1)
MELK (1)
Methionine Adenosyltransferase (MAT) (1)
Hippo pathway (1)
Neprilysin (1)
KLF (1)
PI4K (1)
Aquaporin (1)
SGK (1)
Complement System (1)
NOD (1)
NADPH-oxidase (1)
BMI-1 (1)
Tyrosinase (1)
Imidazoline Receptor (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE