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anti_cancer_approved_drug_library
/library/anti_cancer_approved_drug_library
Anti-Cancer Approved Drug Library
Product No.: L2110

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 1779 approved anti-cancer drugs based on published literatures and database to form this collection that can be used as positive controls in biological cancer investigation and cancer correlation study.

Product No.:L2110
  • A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
  • These FDA, EMA, or NMPA approved anti-cancer drugs have annotated bioactivity, safety, and bioavailability;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
Compound Service
Our compound library can be flexibly customized!View More
Compound library Consultation
Composition of compound library
Others (170)
Adrenergic Receptor (157)
5-HT Receptor (156)
Endogenous Metabolite (140)
Antibacterial (133)
COX (118)
Antibiotic (111)
Dopamine Receptor (104)
Histamine Receptor (103)
Sodium Channel (77)
DNA/RNA Synthesis (76)
Potassium Channel (72)
Calcium Channel (71)
AChR (67)
Parasite (53)
Glucocorticoid Receptor (51)
P450 (43)
HIV Protease (42)
Antifungal (36)
NF-κB (36)
Reactive Oxygen Species (35)
Estrogen/progestogen Receptor (33)
Ferroptosis (33)
EGFR (33)
VEGFR (32)
GABA Receptor (32)
c-Kit (32)
Mitophagy (31)
Topoisomerase (29)
PPAR (29)
Nucleoside Antimetabolite/Analog (29)
PDGFR (29)
SARS-CoV (28)
Dehydrogenase (27)
Estrogen Receptor/ERR (27)
Prostaglandin Receptor (26)
Influenza Virus (26)
PDE (25)
Serotonin Transporter (23)
Microtubule Associated (23)
Norepinephrine (20)
ATPase (19)
Proton pump (19)
iGluR (19)
Androgen Receptor (19)
FLT (18)
DNA Alkylator/Crosslinker (17)
RAAS (17)
HSV (17)
JAK (17)
FGFR (17)
HDAC (17)
Bcr-Abl (16)
Src (15)
c-Met/HGFR (15)
Adenosine Receptor (15)
Virus Protease (15)
Opioid Receptor (15)
TRP/TRPV Channel (14)
HBV (14)
Tyrosine Kinases (14)
Progesterone Receptor (13)
GNRH Receptor (12)
Raf (12)
PKC (12)
CDK (12)
TNF (12)
DHFR (11)
MAO (11)
NMDAR (11)
ROS (11)
SGLT (11)
ALK (11)
Retinoid Receptor (11)
Carbonic Anhydrase (10)
PARP (10)
Antifolate (10)
MRP (10)
Drug Metabolite (10)
P-gp (10)
AChE (10)
HMG-CoA Reductase (10)
Reverse Transcriptase (10)
HCV Protease (9)
Phosphatase (9)
Proteasome (9)
Antifection (9)
AMPK (9)
c-RET (9)
P2Y Receptor (8)
PI3K (8)
BTK (8)
DNA Alkylation (8)
MMP (8)
GluR (8)
Lipoxygenase (8)
CaMK (8)
mTOR (8)
HIF/HIF Prolyl-Hydroxylase (8)
Monoamine Oxidase (8)
Chloride channel (7)
NADPH (7)
ABC (7)
Monoamine Transporter (7)
Guanylate cyclase (7)
Trk receptor (7)
MEK (7)
CFTR (7)
STAT (7)
GPR (7)
Phospholipase (7)
TAM Receptor (7)
Thrombin (7)
HER (7)
Transferase (6)
Mitochondrial Metabolism (6)
ERK (6)
P2X Receptor (6)
BCL (6)
IL Receptor (6)
Interleukin (6)
Hedgehog/Smoothened (6)
Aromatase (6)
Neurokinin receptor (6)
DNA Methyltransferase (6)
S1P Receptor (6)
Histone Methyltransferase (5)
LPL Receptor (5)
Glutathione Peroxidase (5)
PKA (5)
Caspase (5)
ROCK (5)
FXR (5)
Vasopressin Receptor (5)
DNA (5)
Akt (5)
TLR (5)
Endothelin Receptor (5)
ribosome (5)
Nrf2 (5)
HIF (5)
Ras (5)
ROS Kinase (5)
GSK-3 (4)
Melatonin Receptor (4)
Amino Acids and Derivatives (4)
p38 MAPK (4)
Antioxidant (4)
CaSR (4)
Wnt/beta-catenin (4)
Annexin A (4)
Smo (4)
DPP-4 (4)
Fatty Acid Synthase (4)
PGE Synthase (4)
HSP (4)
GPCR19 (4)
Antiviral (4)
IκB/IKK (4)
Beta Amyloid (4)
NO Synthase (4)
Oxytocin Receptor (4)
NOD (4)
Sigma receptor (4)
Tyrosinase (4)
Integrin (3)
Serine Protease (3)
Serine/threonin kinase (3)
UGT (3)
Cysteine Protease (3)
Leukotriene Receptor (3)
Gamma-secretase (3)
MT Receptor (3)
Na-K-Cl cotransporter (3)
CXCR (3)
Xanthine Oxidase (3)
TGF-beta/Smad (3)
Free radical scavengers (3)
Molecular Glues (3)
Isocitrate Dehydrogenase (IDH) (3)
PAK (3)
IGF-1R (3)
Aminopeptidase (3)
GST (3)
c-Fms (3)
cholecystokinin (3)
AhR (3)
Ligand for E3 Ligase (3)
Melanocortin Receptor (3)
Hydroxylase (3)
Adenosine deaminase (3)
Syk (3)
FAK (3)
NOS (2)
Monocarboxylate transporter (2)
ROR (2)
CRM1 (2)
Arginase (2)
Reductase (2)
Cell wall (2)
CAT (2)
Ligands for Target Protein for PROTAC (2)
YAP (2)
LTR (2)
IFNAR (2)
IRE1 (2)
LDL (2)
DNA gyrase (2)
Rho (2)
Aryl Hydrocarbon Receptor (2)
Hexokinase (2)
Somatostatin (2)
Aurora Kinase (2)
Beta-Secretase (2)
Decarboxylase (2)
CCR (2)
Lipid (2)
MAPK (2)
OAT (2)
Ephrin Receptor (2)
CGRP Receptor (2)
Protease-activated Receptor (2)
RSV (2)
GHSR (2)
PLK (2)
Cannabinoid Receptor (2)
Gap Junction Protein (2)
NOD-like Receptor (NLR) (2)
BACE (1)
RAR/RXR  (1)
JNK (1)
TOPK (1)
Thyroid hormone receptor(THR) (1)
Mdm2 (1)
NPC1L1 (1)
Hydrogenase (1)
Na+/Ca2+ Exchanger (1)
Histone Demethylase (1)
Lipase (1)
Factor Xa (1)
VDA (1)
IAP (1)
Adiponectin receptor (1)
Hck (1)
Liver X Receptor (1)
Immunology/Inflammation related (1)
CSF-1R (1)
PAFR (1)
MTH1 (1)
GRK (1)
Glucagon Receptor (1)
Bradykinin Receptor (1)
Chk (1)
cAMP (1)
Thrombopoietin Receptor (1)
Epigenetic Reader Domain (1)
DUB (1)
ATP Citrate Lyase (1)
Glutathione reductase (1)
Sirtuin (1)
PROTAC Linker (1)
FAAH (1)
OX Receptor (1)
PAD (1)
ACK (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
GluCls (1)
Pyroptosis (1)
Neprilysin (1)
PDK (1)
Complement System (1)
Platelet aggregation (1)
NADPH-oxidase (1)
S6 Kinase (1)
p53 (1)
Imidazoline Receptor (1)
PD-1/PD-L1 (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE