Aging is a natural process of becoming older. The causes of aging are assigned to programmed and damage or error theories. The programmed theories imply that aging relies on specific gene regulation, and the damage or error theories emphasize the internal and environmental damages accumulated to living organisms. The damage theories proposed the twelve hallmarks that were generally considered to contribute to the aging process: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, Chronic inflammation, Dysbiosis, Disabled macroautophagy.

There is great interest in finding drugs capable of extending human lifespan and healthspan. Compounds are sought that are capable of modulating multiple aging pathways, thereby preventing a broad-spectrum of age-related diseases. The TargetMol’s Anti-Aging Compound Library, a unique collection of 4880 anti-aging compounds, is an effective tool for anti-aging research, and anti-aging drug screening.