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anti_aging_compound_library
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Anti-Aging Compound Library
Product No.: L8200

Aging is a natural process of becoming older. The causes of aging are assigned to programmed and damage or error theories. The programmed theories imply that aging relies on specific gene regulation, and the damage or error theories emphasize the internal and environmental damages accumulated to living organisms. The damage theories proposed the twelve hallmarks that were generally considered to contribute to the aging process: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, Chronic inflammation, Dysbiosis, Disabled macroautophagy.

There is great interest in finding drugs capable of extending human lifespan and healthspan. Compounds are sought that are capable of modulating multiple aging pathways, thereby preventing a broad-spectrum of age-related diseases. The TargetMol’s Anti-Aging Compound Library, a unique collection of 3279 anti-aging compounds, is an effective tool for anti-aging research, and anti-aging drug screening.

Product No.:L8200
  • A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets cover various aging-related processes, such as cell protective, DNA damage repair, and stem cell induction, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;
Compound Service
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Compound library Consultation
Composition of compound library
NF-κB (165)
PI3K (128)
DNA/RNA Synthesis (128)
Reactive Oxygen Species (121)
P450 (120)
Antibiotic (120)
mTOR (90)
Antioxidant (86)
CDK (82)
TNF (77)
ERK (76)
AMPK (75)
HDAC (74)
Antifungal (71)
p38 MAPK (69)
Parasite (68)
HIV Protease (66)
JAK (65)
Akt (63)
PPAR (60)
Epigenetic Reader Domain (60)
Ferroptosis (57)
Topoisomerase (56)
Influenza Virus (55)
STAT (55)
Mitochondrial Metabolism (54)
Mitophagy (53)
Sirtuin (51)
Histone Methyltransferase (48)
Estrogen/progestogen Receptor (47)
Wnt/beta-catenin (47)
PARP (45)
Prostaglandin Receptor (43)
BCL (42)
Microtubule Associated (40)
JNK (39)
Calcium Channel (38)
SARS-CoV (38)
NO Synthase (38)
ROS (37)
EGFR (37)
GSK-3 (36)
Caspase (36)
PKC (36)
IGF-1R (36)
p53 (36)
Virus Protease (35)
Nucleoside Antimetabolite/Analog (35)
IL Receptor (35)
HSP (35)
Dehydrogenase (34)
MMP (33)
AChR (33)
Estrogen Receptor/ERR (32)
Tyrosine Kinases (32)
VEGFR (32)
TGF-beta/Smad (32)
Potassium Channel (32)
FLT (32)
Tyrosinase (32)
HSV (31)
DNA-PK (30)
Src (30)
Aurora Kinase (30)
Glucocorticoid Receptor (28)
IκB/IKK (28)
Adrenergic Receptor (27)
5-HT Receptor (27)
HIF/HIF Prolyl-Hydroxylase (26)
Proteasome (25)
Nrf2 (25)
ALK (25)
MEK (25)
E1/E2/E3 Enzyme (24)
Lipoxygenase (24)
ROCK (23)
NOS (22)
HCV Protease (22)
PKA (22)
PDGFR (22)
DUB (22)
Casein Kinase (22)
FGFR (22)
S6 Kinase (22)
AChE (21)
PDE (20)
Gamma-secretase (20)
Beta Amyloid (20)
Histamine Receptor (19)
Hedgehog/Smoothened (19)
ATM/ATR (19)
Interleukin (18)
MAPK (18)
Sodium Channel (18)
Mdm2 (17)
Carbonic Anhydrase (17)
Dopamine Receptor (17)
DNA Alkylator/Crosslinker (17)
Histone Demethylase (17)
TRP/TRPV Channel (17)
GABA Receptor (17)
Bcr-Abl (16)
Reverse Transcriptase (16)
c-Kit (16)
ATPase (15)
Phospholipase (15)
HIF (15)
Phosphatase (14)
MAO (14)
Raf (14)
NADPH (13)
PERK (13)
HBV (13)
Cysteine Protease (13)
Smo (13)
P-gp (13)
PLK (13)
Anti-infection (13)
c-Met/HGFR (12)
Progesterone Receptor (12)
Serine/threonin kinase (12)
Drug Metabolite (12)
DNA Alkylation (12)
Chk (12)
TLR (12)
Trk receptor (12)
FAK (12)
Glutathione Peroxidase (11)
Antifolate (11)
Monoamine Oxidase (11)
BACE (10)
RAAS (10)
Serine Protease (10)
DNA gyrase (10)
Antiviral (10)
PDK (10)
Syk (10)
DNA Methyltransferase (10)
Ras (10)
Kinesin (10)
Adenosine Receptor (9)
IRE1 (9)
DPP-4 (9)
DNA (9)
Telomerase (9)
PGE Synthase (9)
Histone Acetyltransferase (9)
transporter (9)
Retinoid Receptor (9)
c-RET (9)
NOD (9)
DHFR (8)
Pim (8)
iGluR (8)
CXCR (8)
Androgen Receptor (8)
LRRK2 (8)
GPR (8)
Thrombin (8)
NOD-like Receptor (NLR) (8)
CAT (7)
Reductase (7)
IAP (7)
PAK (7)
Xanthine Oxidase (7)
CaMK (7)
Porcupine (7)
HER (7)
Chloride channel (6)
Proton pump (6)
UGT (6)
BTK (6)
Antifection (6)
Opioid Receptor (6)
Fatty Acid Synthase (6)
PTEN (6)
Beta-Secretase (6)
ROS Kinase (6)
Transferase (5)
Amino Acids and Derivatives (5)
Lipase (5)
Factor Xa (5)
MRP (5)
Glucokinase (5)
Aryl Hydrocarbon Receptor (5)
RIP kinase (5)
NMDAR (5)
GluR (5)
Free radical scavengers (5)
Ligand for E3 Ligase (5)
ribosome (5)
CRISPR/Cas9 (5)
NADPH-oxidase (5)
HMG-CoA Reductase (5)
TAM Receptor (5)
p97 (5)
YAP (4)
IFNAR (4)
DYRK (4)
OCT (4)
Serotonin Transporter (4)
LIM Kinase (4)
FXR (4)
PYK2 (4)
Immunology/Inflammation related (4)
SIK (4)
P2X Receptor (4)
Glucosidase (4)
CCR (4)
Epoxide Hydrolase (4)
Norepinephrine (4)
RSV (4)
GST (4)
c-Fms (4)
Aromatase (4)
PI4K (4)
Cannabinoid Receptor (4)
MLK (4)
Integrin (3)
Dynamin (3)
Ligands for Target Protein for PROTAC (3)
Arginase (3)
P2Y Receptor (3)
TOPK (3)
ABC (3)
cell cycle arrest (3)
Leukotriene Receptor (3)
Annexin A (3)
MTH1 (3)
GRK (3)
Hexokinase (3)
Molecular Glues (3)
Guanylate cyclase (3)
FAAH (3)
OXPHOS (3)
Acyltransferase (3)
SGK (3)
BMI-1 (3)
AhR (3)
S1P Receptor (3)
advanced glycation end products (2)
NPC1L1 (2)
Monocarboxylate transporter (2)
ROR (2)
LPL Receptor (2)
Tie-2 (2)
Melatonin Receptor (2)
Rho (2)
Liver X Receptor (2)
NAMPT (2)
Glutaminase (2)
CSF-1R (2)
Myosin (2)
FLAP (2)
LDL (2)
APC (2)
ACK (2)
KSP (2)
SGLT (2)
ATP Citrate Lyase (2)
Wee1 (2)
Lipid (2)
Survivin (2)
MNK (2)
OAT (2)
STING (2)
ASK (2)
GluCls (2)
PAI-1 (2)
Neprilysin (2)
Carboxypeptidase (2)
GPX (2)
Adenosine deaminase (2)
Platelet aggregation (2)
IRAK (2)
Sigma receptor (2)
lysosomal autophagy (2)
CFTR (2)
Imidazoline Receptor (2)
PKM (2)
Thyroid hormone receptor(THR) (1)
Adenylyl cyclase (1)
GSNOR (1)
Transaminase (1)
stilbene oxidase (1)
Hydrogenase (1)
MALT (1)
CYP19A1 (1)
MyD88 (1)
LTR (1)
Na+/Ca2+ Exchanger (1)
aconitase (1)
RAR/RXR  (1)
VDA (1)
CaSR (1)
N-Acetylglucosaminyltransferase (1)
Stemness kinase (1)
RANKL/RANK (1)
Amylase (1)
IDO (1)
Adiponectin receptor (1)
PAFR (1)
Glucagon Receptor (1)
Anion Exchanger (1)
Integrase (1)
PROTAC Linker (1)
Bombesin Receptor (1)
Thioredoxin (1)
Stearoyl-CoA Desaturase (SCD) (1)
Somatostatin (1)
PAD (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
BCRP (1)
Glutathione reductase (1)
Aminopeptidase (1)
Ephrin Receptor (1)
hCE (1)
Pyroptosis (1)
Hippo pathway (1)
KLF (1)
Hydroxylase (1)
Complement System (1)
Gap Junction Protein (1)
Discoidin Domain Receptor (DDR) (1)
cholecystokinin (1)
Protease-activated Receptor (1)
PD-1/PD-L1 (1)
Example of compound library information
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE